研究興趣 (Research Interests)：
(1)結構分析與反應機制探討 (Structural Analysis and Research on the Reaction Mechanism)。 (2)藥物設計合成與材料科學 (Drug Design and Synthesis and Materials Science)。 (3)中醫藥學研究與健康促進 (Traditional Pharmaceutical Research and Health Promotion)。
期刊雜誌編審 (journals editorial)：
Journal of Heterocyclic Chemistry (USA; WILEY-BLACKWELL)、Monatshefte fur Chemie – Chemical Monthly (Austria; SPRINGER WIEN)、Current Organic Synthesis (United Arab Emirate; BENTHAM SCIENCE PUBL LTD)、Molecules
(Switzerland; Multidisciplinary Digital Publishing Institute (MDPI) )、Crystals (Switzerland; MDPI)、Molbank (Switzerland; MDPI)、Marine Drugs (Switzerland; MDPI)、Biomolecules (Switzerland; Multidisciplinary Digital Publishing Institute (MDPI) )。
研究論文 (Research Papers)：
包括 (Include): 結構分析 (Structural Analysis)、反應機制探討 (Research on the Reaction Mechanism)、藥物設計合成 (Drug Design and Synthesis)、材料科學 (Materials Science)、中醫藥學研究 (Traditional Pharmaceutical Research)、健康促進 (Health Promotion)。
審閱論文 (Referred Papers)：
Long-Chih Hwang*, Shiun-Yau Yang, Chung-Lin Chuang and Gene-Hsiang Lee, “An Optimized Synthesis, Molecular Structure and Characterization of Benzylic Derivatives of 1,2,4-Triazin-3,5(2H,4H)-dione”, Molecules, 2017, 22(11), 1924.
G.H. Lee, L.C. Hwang*, “Crystal Structure of 2-[(2-Acetoxyethoxy)methyl]-3-amino-1,2,4-triazin-5(2H)-one”, International Journal of Advanced Chemistry, 2017, 5(1), 35-38.
Long-Chih Hwang*, Chung-Lin Chuang, and Gene-Hsiang Lee, “Packing of Two Independent Molecules: 3-Amino-2-benzyl-6-bromo-1,2,4-triazin-5(2H)-one”, X-ray Structure Analysis Online, 2016, 32(7), 33-34.
Hung-Chou Wu, Jean-Ho Chu, Chin-Wei, Li, Long-Chih Hwang, and Ming-Jung Wu*, “Palladium-Catalyzed Regioselective Arylation of Pyrazolo[1,5-a]pyridines via C-H Activation and Synthetic Applications on P38 Kinase Inhibitors”, Organometallics, 2016, 35, 288-300.
Hung-Chou Wu, Chia-Wen Yang, Long-Chih Hwang, and Ming-Jung Wu*, “Au(I)-Catalyzed and Iodine-Mediated Cyclization of Enynylpyrazoles to Provide Pyrazolo[1,5-a]pyridines”, Organic & Biomolecular Chemistry, 2012, 10, 6640-6648.
T.-P. Wang*, L.-L. Chang, S.-N. Chang, E.-C. Wang, L.-C. Hwang, Y.-H. Chen, and Y.-M. Wang, “Successful Preparation and Characterization of Biotechnological Grade Agarose from Indigenous Gelidium amansii of Taiwan”, Process Biochem., 2012, 47, 550-554.
Wang, Tzu-Pin*; Su, Yu-Chih; Chen, Yi; Liou, Yi-Ming; Lin, Kun-Liang; Wang, Eng-Chi; Hwang, Long-Chih; Wang, Yun-Ming; and Chen, Yen-hsu, “In vitro Selection and Characterization of a Novel Zn(II)-Dependent Phosphorothiolate Thiolesterase Ribozyme”, Biochemistry, 2012, 51, 496-510.
Hung-Chou Wu, Long-Chih Hwang, and Ming-Jung Wu*, “A copper-mediated cyclization reaction of hydrazine with enediynones providing pyrazolo[1,5-a]pyridines”, Organic & Biomolecular Chemistry, 2011, 9, 670-672.
Long-Chih Hwang*, Yu-Chih Su, Tzu-Pin Wang, Li-The Liu, and Gene-Hsiang Lee, “Crystal Structure of 3-Amino-2-benzyl-6-bromo-1,2,4-triazin-5(2H)-one”, X-ray Structure Analysis Online, 2010, 26(8), 61-62.
Tzu-Pin Wang,* Yi-Jang Chiou, Yi Chen, Eng-Chi Wang, Long-Chih Hwang, Bing-Hung Chen, Yen-Hsu Chen, and Chun-Han Ko, “Versatile Phosphoramidation Reactions for Nucleic Acid Conjugations with Peptides, Proteins, Chromophores, and Biotin Derivatives”, Bioconjugate Chem., 2010, 21, 1642-1655.
Long-Chih Hwang*, Li-Teh Liu, Yu-Chih Su, and Gene-Hsiang Lee, “Crystal Structure of 6-Bromo-1,2,4-triazin-3,5(2H,4H)-dione”, Analytical Sciences, 2008, 24, x201-x202.
T.H. Wei, C.W. Chen, L.C. Hwang, P.L. Tu, and T.C. Wen*, “Room temperature luminescence in CuI/AgI quantum dots”, J. of Luminescence, 2008, 128, 161-165.
Hsiang-Wen Chen, Hung-Tien Kuo, Long-Chih Hwang, Mei-Fang Kuo, and Rei-Cheng Yang*, “PROTEOMIC ALTERATION OF MITOCHONDRIAL ALDEHYDE DEHYDROGENASE 2 IN SEPSIS REGULATED BY HEAT SHOCK RESPONSE”, SHOCK, 2007, 28, 710-716.
L. C. Hwang, T. H. Wei, Y. L. Hsia, C. M. Li, P. L. Tu, and T.C. Wen*, “Photoluminescence of I-VII Semiconductor Compounds. Sensitized Luminescence from “Deep States” Recombination in CuBr/AgBr Nanocrystals”, J. Chin. Chem. Soc., 2006, 53, 1235-1241.
Yen-Hsiung Liao*, Long-Chih Hwang, Jing-Shwu Kao, Shuenn-Jiun Yiin, Shu-Fang Lin, Chia-Hong Lin, Yu-Cheng Lin, Tar-Ching Aw, “Lipid Peroxidation in Workers Exposed to Aluminium, Gallium, Indium, Arsenic, and Antimony in the Optoelectronic Industry”, J. Occup. Environ. Med., 2006, 48, 789-793.
Long-Chih Hwang*, Chun-Hsien Tu, and Jung-Hui Wang, “Aromatization and Ring Cyclization: A Reasonable Understanding on the Ring Cyclization Mechanism of 3-Amino-6-hydrazino-1,2,4-triazin-5(2H)-one Reacted with One-carbon Fragment Reagents or Nitrous Acid”, J. Heterocyclic Chem., 2006, 43, 889-895.
Long-Chih Hwang*, Shin-Yi Jane, Hsing-Yi Lai, Chun-Hsien Tu, and Gene-Hsiang Lee, “Synthesis, Molecular Structure and Characterization of Allylic Derivatives of 6-Amino-3-methyl-1,2,4-triazolo[3,4-f][1,2,4]triazin-8(7H)-one”, Molecules, 2006, 11, 444-452.
T.H. Wei, T.C. Wen*, L.C. Hwang, S.C. Lee, W.Y. Chou, S.J. Hu, J.H. Wang, “Optical nonlinearity and photoluminescence in CuI doped glass”, Optical Materials, 2006, 28, 569-573.
Long-Chih Hwang*, Chun-Hsien Tu, Jung-Hui Wang, and Gene-Hsiang Lee, “Synthesis and Molecular Structure of 6-Amino-3-benzylmercapto-1,2,4-triazolo[3,4-f][1,2,4]triazin- 8(7H)-one”, Molecules, 2006, 11, 169-176.
Long-Chih Hwang*, Rang-Rong Wu, and Chun-Hsien Tu, “Aromatization and Ring Cyclization: A better understanding on the ring cyclization mechanism of 3-amino- 6-hydrazino-1,2,4-triazin-5-(2H)-one reacted with acetic acid in N,N-dimethylformamide”, Journal of Heterocyclic Chemistry, 2005, 42, 851-855.
L.C. Hwang*, R.R. Wu, S.Y. Jane, and G.H. Lee, “Crystal Structure of 3-Amino-1,2,4-triazine”, Analytical Sciences, 2003, 19, x73-x74.
L.C. Hwang, S.C. Lee, and T.C. Wen*, “Nonlinear absorption and refraction in lead glasses: enhanced by the small metal particle dispersion”, Optic Communications, 2003, 228, 373-380.
Yen-Hsiung Liao*, Long-Chih Hwang, Chih-Ching Chang, Yu-Jue Hong, I-Nong Lee, Jen-Hsuan Huang, Shu-Fang Lin, Maurice Shen, Chia-Hong Lin, Yung-Yen Gau, and Chin-Tzo Yang, “Building Collapse and Human Deaths Resulting from the Chi-Chi Earthquake in Taiwan, September 1999”, Archives of Environmental Health, 2003, 58 (9), 572-578.
T.C. Wen*, L.C. Hwang, W.Y. Lin, C.H. Chen, and C.H. Wu, “Nonlinear absorption of light: two-photon absorption and optical saturation in metalloporphyrin-doped boric acid glass”, Chemical Physics, 2003, 286, 293-302.
T.C. Wen*, L.C. Hwang, and W.Y. Lin, “Nonlinear Light Absorption in Porphyrin Derivatives Including the Complexes of the IIIa Metal Group”, Journal of Chinese Chemical Society, 2002, 49, 875-881.
L.C. Hwang*, Chun-Hsien Tu, Jung-Hui Wang, Gene-Hsiang Lee, and Yu Wang, “Crystal Structure of 6-Amino-3-ethyl-1,2,4-triazolo[3,4-f][1,2,4]triazin- 8(7H)-one”, Analytical Sciences, 2002, 18, 853-854.
L.C. Hwang*, Jung-Hui Wang, Cherng-Chyi Tzeng, Gene-Hsiang Lee, and Shie-Ming Peng, “Crystal Structure of 3-Amino-1,2,4-triazin-5(2H)-one”, Analytical Sciences, 2002, 18, 723-724.
L.C. Hwang, C.Y. Tsai, C.J. Tiao, and T.C. Wen*, “Optic Nonlinearities of a Copper Complex of Pyrazinoporphyrazine”, Optical and Quantum Electronics, 2000, 32, 641-656.
C.J. Tiao, L.C. Hwang, and T.C. Wen*, “Two-Photon Absorption and Excited-State Refractions in Anthraquinone Dyes”, J. Chin. Chem. Soc., 1998, 45, 659-665.
T.C. Wen*, C.J. Tiao, L.C. Hwang, and C.Y. Tsai, “Synthesis and Third-Order Nonlinear Optical Properties of Liner p-Acenequinones”, Synthetic Metals, 1998, 92, 235-243.
T.C. Wen*, S.J. Jen, H.W. Liu, L.C. Hwang, and I.D. Lian, “Optical Nonlinearities of Phthalocyanines and Naphthalocyanines”, J. Chin. Chem. Soc., 1996, 43, 123-132.
C.C. Tzeng*, L.C. Hwang, C.C. Chen, and D.C. Wei, “Synthesis of Racemic 5-Substituted 1-(2,3-Dihydroxypropyl)-5-substituted-6-azauracils and Their Isosterric Isomers”, Nucleosides & Nucleotides, 1995, 14, 1425-1435.
L.C. Hwang, C.J. Wang, G.H. Lee, Y. Wang, and C.C. Tzeng*, “Synthesis and Structure Assignment of 1-[(2-Hydroxy-ethoxy)methyl]- and 1-[(1,3-Dihydroxy- 2-propoxy)methyl]- 6-azaisocytosine”, Heterocycles, 1995, 41, 293-301.
L.C. Hwang, E.C. Wang, K.H. Lee, and C.C. Tzeng*, “Synthetic and Antiviral Studies on Certain Acyclonucleosides of 5-Substituted-6-azauracils”, Chin. Pharm. J., 1995, 47, 1-11.
L.C. Hwang, D.C. Wei, M.C. Cheng, Y. Wang, and C.C. Tzeng*, “Synthesis and Structure Assignment of 1-(2-Acetoxyethoxy)methyl Derivatives of 5-Chloro-6-azauracil and 5-Bromo-6-azaisocytosine”, Nucleosides & Nucleotides, 1995, 13, 2185-2193.
D.C. Wei, L.C. Hwang, and C.C. Tzeng*, “Condensed as-Triazine: Synthesis of Imidazo[4,5-e]-as-triazine 1-Oxides (6-Azapurine 6-Oxides) as Guanine and Hypoxanthine Analogues”, Heterocycles, 1994, 38, 2009-2015.
C.C. Tzeng*, D.C. Wei, L.C. Hwang, M.C. Cheng, and Y. Wang, “Condensed 1,2,4-Triazines: Synthesis of 5-Benzyl-5H-imidazo[4,5-e]1,2,4-triazine 1-Oxides (9-Benzyl-6-azapurine 6-Oxides)”, J. Chem. Soc. Perkin Trans., 1994, 1, 2253-2256.
L.C. Hwang, D.C. Wei, C.H. Han, K.H. Lee, and C.C. Tzeng*, “Condensed as-Triazines. Part 4. Synthesis of 2-Amino-9-benzyl-6-azapurine (3-Amino-5-benzyl-5H-imidazo[4,5-e]- as-triazine)”, J. Chem. Research (S), 1994, 121.; J. Chem. Research (M), 1994, 0831-0842.
D.C. Wei, L.C. Hwang, C.H. Han, K.H. Lee, and C.C. Tzeng*, “Condensed as-Triazine III: Synthesis of 2-Amino-6-azapurine (3-Aminoimidazo[4,5-e]- as-triazine) as a Potential Antitumor Agent”, Heterocycles, 1993, 36, 2733-2743.