研究著作

Paper published (2012-2009)

  1. Chen, Po-Yuan; Huang, Keng-Shiang; Tsai, Chin-Chuan; Wang, Tzu-Pin; Wang, Eng-Chi* “Pd(II)-Mediated Cyclization of o-Allylbenzaldehydes in Water: A Novel Synthesis of Isocoumarins”

Org. Lett. 2012, 14, 4930-4933.

  1. Chen, Hsing-Ming; Chen, Po-Yuan; Wang, Chih-Feng; Tsai, Jui-Chi; Wang, Eng-Chi* “An improved method for the conversion of oxiranes to thiiranes and the discrimination of their base peaks in

EI-MS ARKIVOC (Gainesville, FL, United States), 2012, 8, 157-168.

  1. Wang, Eng-Chi*; Tsai, Jui-Chi; Li, Sie-Rong; Chen, Po-Yuan “Method for preparing coumarin and chromene compounds “ U.S. Pat. Appl. Publ. 2012, US 20120088923 A1 20120412
  2. Chen, Po-Yuan; Chen, Hsing-Ming; Chiang, Michael Y.; Wang, You-Feng; Li, Sie-Rong; Wang, Tzu-Pin; Wang, Eng-Chi* “A novel and chemoselective synthesis of substituted

3,4-dihydroisoquinolin-1(2H)-ones from o-oxiranylmethylbenzonitrile intermediates and TBAB/NaCN” Tetrahedron 2012, 68, 3030-3036.

  1. Wang, Tzu-Pin*; Su, Yu-Chih; Chen, Yi; Liou, Yi-Ming; Lin, Kun-Liang; Wang, Eng-Chi; Hwang, Long-Chih; Wang, Yun-Ming; Chen, Yen-Hsu “

In Vitro Selection and Characterization of a Novel     Zn(II)-Dependent Phosphorothiolate Thiolesterase Ribozyme “ Biochemistry 2012, 51, 496-510.

  1. Wang, Tzu-Pin*; Chang, Li-Lin; Chang, Sheng-Nan; Wang, Eng-Chi; Hwang, Long-Chih; Chen, Yen- Hsu; Wang, Yun-Ming “Successful preparation and characterization of biotechnological grade

agarose from indigenous Gelidium amansii of Taiwan” Process Biochemistry (Oxford, United Kingdom) 2012, 47, 550-554.

  1. Chen, Po-Yuan; Wang, Tzu-Pin; Huang, Keng-Shiang; Kao, Chai-Lin; Tsai, Jui-Chi; Wang, Eng-Chi*

“tert-BuOK-mediated carbanion-yne intramolecular cyclization: synthesis of 2-substituted 3-benzyl-Benzofurans” Tetrahedron 2011, 67, 9291-9297.

  1. Chen, Po-Yuan; Wang, Tzu-Pin; Chiang, Michael Y.; Huang, Keng-Shian; Tzeng, Cherng-Chyi; Chen, Yi-Long; Wang, Eng-Chi* “environmentally benign syntheses of flavanones” Tetrahedron

2011, 67, 4155-4160.

  1. Chen, Liang-Yeu; Li, Sie-Rong; Chen, Po-Yuan; Chang, Ho-Chiang; Wang, Tzu-Pin; Tsai, Ian-Lih; Wang, Eng-Chi* “2,3-dichloro-5,6-dicyanobenzoquinone (DDQ) mediated 

oxidation-dehydrogenation of 2-aroyl-3,4-dihydro-2H-benzopyrans: synthesis of 2-aroylbenzopyran-4-ones” ARKIVOC (Gainesville, FL, United States) 2010, 11, 64-76.

10.     Wang, Tzu-Pin*; Chiou, Yi-Jang; Chen, Yi; Wang, Eng-Chi; Hwang, Long-Chih; Chen, Bing-Hung; Chen, Yen-Hsu; Ko, Chun-Han “Versatile Phosphoramidation Reactions for Nucleic Acid    

Conjugations with Peptides, Proteins, Chromophores, and Biotin Derivatives” Bioconjugate Chemistry 2010, 21, 1642-1655.

  1. Wang, E.-C.; Li, S.-R.  “ Intermediate compounds and processes for the preparation of 7-benzyloxy-3-(4-methoxyphenyl)-2H-1-benzopyran”. U.S. Pat. Appl. Publ. (2010), 6pp.  CODEN:

USXXCO US 2010298582 A1 20101125 AN 2010:1465099.

  1. Wang, Eng-Chi; Li, Sie-Rong. “Processes for preparing isoflavonoids using 7-benzyloxy-3-(4-methoxyphenyl)-2H-1-benzopyran as a starting material”. U.S. Pat. Appl. Publ. (2010), 11pp.  CODEN: USXXCO US 2010298581 A1 20101125 AN 2010:1465096.
  2. Chen, L.-Y.; Li, S.-R.; Chen, P.-Y.; Chang, H.-C.; Wang, T.-P.; Tsai, I.-L.; Wang, E.-C.*  ARKIVOC (Gainesville, FL, United States)  2010,  11,  64-76.
  3. Wang, T.-P.; Chiou, Y.-J.; Chen, Y.; Wang, E.-C.; Hwang, L.-C.; Chen, B.-H.; Chen, Y.-H.; Ko, C.-H. Bioconjugate Chem. 2010, 21, 1642-1655.
  4. Tsai, J.-C.; Li, S-R.; Chiang, Michael Y.; Chen, L.-Y.; Chen, P. Y.; Lo, Y.-F.; Wang, C.-H.; Lin, C.-N. Wang, E.-C.* “A novel synthesis of 3-alkoxymethylcoumarins from 3-cyanochromenes via 2-phenylimino-3-alkoxymethylchromenes intermediates” J. Org. Chem. 2009, 74, 8789-8801.
  5. Li, S-R.; Shu, C.-J.; Chen, L.-Y.; Chen, H.-M.; Chen, P. Y.;Wang, E.-C.* “Synthesis of substituted 2-aroyl-3-methylchromen-4-ones from isovanillin via 2-aroyl-3- methylchroman intermediates” Tetrahedron 2009, 65, 8702-8707.
  6. Chen, L.-Y.; Li, S-R.; Chen, P. Y.; Tsai, I.-L.; Hsu, C. L.; Lin, H. P.; Wang, T. P.;Wang, E.-C.* “A novel carbanion-olefin intramolecular cyclization: synthesis of substituted 2-aroyl-1-dihydrobenzopyrans from salicylaldehydes” Tetrahedron Lett.2009, 50, 5748-575
  7. Li, S-R.; Chen, P. Y.; Chen, P. Y.; Lo, Y.-F.; Tsai, I.-L.; Wang, E.-C.* “Synthesis of haginin E, equol, daidzein, and formononetin from resorcinol via isoflavene intermediates” Tetrahedron Lett. 2009, 50, 2121-2123.
  8. Lin, Y. S.; Huang, K. S.;* Yang, C. H.;* Wang, E.-C.* Jhong, J. Y.; Hsu, C. J.; Kuo, C. Y. “Precise control of chitosan microparticles using a double T-junction microchannel chip: facile separation of satellite drops” LAB CHIP, 2009, 9, 145-150.
  9. Tsai, J.-C.; Li, S-R.; Chen, L.-Y.; Chen, P. Y.; Jhong, J. Y.; Shu, C.-J.; Lo, Y.-F.; Lin, C.-N. Wang, E.-C.* “Synthesis of 3-aryl-2,5-dihydro-1-benzoxepines from Phenol via ring-closing metathesis” J. Chin. Chem. Soc. 2008, 55, 1317-1321.
  10. Tsai, J.-C.; Li, S-R.; Chen, L.-Y.; Chen, P. Y.;  Hsu, Sodio C.-N.; Lin, C.-N.; Wang, E.-C..* “Synthesis of substituted 2,5-dihydro-1-naphthoxepines from 1-naphthol via ring-closing metathesis” ARKIVOC (Gainesville, FL, United States) 2008, 12, 205-217.
  11. Lin, G.-T.; Tseng, H.-F.; Chang, C.-K.; Chuang, L.-Y.; Liu, C.-S.; Yang, C.-H.; Tu, C.-J.; Wang, E.-C.; Tan, H.-F.; Chang, C.-C.; Wen, C.-H.; Chen, H.-C.; Chang, H.-W. “SNP combinations in chromosome-wide genes are associated with bone mineral density in Taiwanese women”. Chin. J. Physiol. 2008, 51, 32-41.
  12. Li, S-R.; Chen, H.-M.; Chen, P. Y.;  Tsai, J.-C.; Chen, L.-Y.; Wang, E.-C.;* Huang, Y.-T.; Wei, Y.-C.; Lu, P.-J.. “Synthesis and evaluation of the cytotoxicities of neoflavenes.” J. Chin. Chem. Soc. 2008, 55, 923-932.
  13. Li, S-R.; Chen, H.-M.; Chen, L.-Y.; Tsai, J.-C.; Chen, P. Y.; Hsu, Sodio C.-N.; Wang, E.-C..* “Synthesis of 1-benzoxepin-5-ones (ols) from salicylaldehydes via ring-closing metathesis” ARKIVOC (Gainesville, FL, United States) 2008, 2, 172-182.
  14. Li, S-R.; Chen, L.-Y.; Tsai, J.-C.; Tzeng, J. Y.; Tsai, I. L.; Wang, E.-C.* “New syntheses of dalbergichromene and dalbergin from vanillin via neoflavene intermediate.” Tetrahedron Lett. 2007, 48, 2139-2141.
  15. Wang, E.-C.; Wu, C. H. ; Chien, S. C. ; Chiang, W. C.;  Kuo, Y. H.* “An efficient and chemoselective deprotection of aryl- and styrenyldithioketals (acetals).” Tetrahedron Lett. 2007, 48, 7706-7708.
  16. Li, S-R.; Chen, L.-Y.; Tsai, J.-C.; Tzeng, J. Y.; Tsai, I. L.; Wang, E.-C.* “New syntheses of dalbergichromene and dalbergin from vanillin via neoflavene intermediate.” Tetrahedron Lett. 2007, 48, 2139-2141.
  17. Chen, P. Y.; Chen, H. M.; Chen, L. Y.; Tzeng, J. Y.;  Tsai, J. C.; Chi, P. C.; Li, S. R.;  Wang, E. C. * “Claisen rearrangement/Baylis-Hillman reaction/ring-closing metathesis as bases for the construction of substituted cyanonaphthalenes.” Tetrahedron 2007, 63, 2824-2828.
  18. Wang, E. C.; Wein, Y. S.; Kuo, Y. H.*, “A concise and efficient Synthesis of Salvinal from Isoeugenal via a Phenoxenium ion Intermediate”Tetrahedron Lett. 2006, 47, 9195-9197.
  19. Hou, D. R.*; Cheng, H. Y.; Wang, E. C. “Efficient Synthesis of Oncinotine and Neooncinotine” J. Org. Chem. 2004, 69, 6094-6099.
  20. Tsai, T. W. ; Wang, E. C.*; Li, S. R.;  Chen, H. M.; Lin, Y. L.;  Wang, Y. F.; Huang, K.S. “A New Synthesis of Benzofurans from Phenols via Claisen Rearrangement and Ring-Closing Metathesis ”J. Chin. Chem. Soc. 2004, 51(6), 1307-1318.
  21. Tsai, T. W.; Wang, E. C.* “A new synthesis of angelicin from 7-hydroxycoumarin via C-propenation-O-vinylation and ring-closing metathesis” J. Chin. Chem. Soc. 2004, 51(5), 1019-1024.
  22. Wang, E. C.*; Huang, K. S.; Chen, H. M.; Wu, C. C.;  Lin, G. J.  “An efficient method for the preparation of nitriles via the dehydration of aldoximes with phthalic anhydride”J. Chin. Chem. Soc. 2004, 51 (3), 619-627.
  23. Hou, D. R.*; Cheng, H. Y.; Wang, E. C. “Efficient Synthesis of Oncinotine and Neooncinotine” J. Org. Chem. 2004, 69, 6094-6099.
  24. Huang, K. S.; Wang, E. C.* “Synthesis of Substituted Indenes from Isovanillin via Claisen Rearrangement and RCM” J. Chin. Chem. Soc. 2004, 51, 383-391.
  25. Huang, K. S.; Wang, E. C.*; Chen, H. M.  “Synthesis of 4-Alkoxy-3-methoxy – 5H- benzocycloheptenes and 2-Alkoxy-3-methoxy-5H-benzocycloheptenes”J. Chin, Chem. Soc. 2004, 51, 807-816.
  26. Tsai, T. W.; Wang, E. C.*; Huang, K. S.; Li, S. R. ; Wang , Y. F. ; Lin, Y. L. ; Chen, Y. H. “Synthesis of Benzofurans from Isovanillin via C-propenylation-O-vinylation and Ring-closing metathesis” Heterocycles
  27. Huang, K. S.; Wang, E. C.*; Chen, H. M.  “Synthesis of Naphthalenes and   Naphthols” J. Chin. Chem. Soc. 2004, 51, 585-605.
  28. Wang, E. C.*; Chen, H. F. ; Feng, P. K. ; Lin, Y. L.; Hsu, M. K. “A New Synthesis of 3-Alkyl-1-Isoindolinones” Tetrahedron Lett. 2002, 43(50), 9163-9165.
  29. Huang, K. S.; Wang, E. C.* “A Novel Synthesis of Substituted Naphthalenes via Claisen Rearrangement and RCM Reaction” Tetrahedron Lett. 2001, 42, 6155-6157.