{"id":41,"date":"2016-09-11T01:23:06","date_gmt":"2016-09-10T17:23:06","guid":{"rendered":"http:\/\/wp.kmu.edu.tw\/lnchhw\/?page_id=41"},"modified":"2021-05-20T01:51:13","modified_gmt":"2021-05-19T17:51:13","slug":"%e7%a0%94%e7%a9%b6%e8%88%87%e8%91%97%e4%bd%9c-research-publication","status":"publish","type":"page","link":"https:\/\/wp.kmu.edu.tw\/lnchhw\/%e7%a0%94%e7%a9%b6%e8%88%87%e8%91%97%e4%bd%9c-research-publication\/","title":{"rendered":"\u7814\u7a76\u8207\u8457\u4f5c (Research & Publication)"},"content":{"rendered":"

\u7814\u7a76\u8208\u8da3<\/strong> (Research Interests)<\/strong>\uff1a
\n<\/strong> (1)\u7d50\u69cb\u5206\u6790\u8207\u53cd\u61c9\u6a5f\u5236\u63a2\u8a0e (Structural Analysis and Research on the Reaction Mechanism)\u3002 (2)\u85e5\u7269\u8a2d\u8a08\u5408\u6210\u8207\u6750\u6599\u79d1\u5b78 (Drug Design and Synthesis and Materials Science)\u3002 (3)\u4e2d\u91ab\u85e5\u5b78\u7814\u7a76\u8207\u5065\u5eb7\u4fc3\u9032 (Traditional Pharmaceutical Research and Health Promotion)\u3002<\/p>\n

\u671f\u520a\u96dc\u8a8c\u7de8\u5be9<\/strong> (journals editorial)<\/strong>\uff1a
\n<\/strong> Journal of Heterocyclic Chemistry\u00a0<\/em>(USA; WILEY-BLACKWELL)\u3001Monatshefte fur Chemie – Chemical Monthly\u00a0<\/em>(Austria; SPRINGER WIEN)\u3001Current Organic Synthesis\u00a0<\/em>(United Arab Emirate; BENTHAM SCIENCE PUBL LTD)\u3001Molecules<\/em>
\n(Switzerland; Multidisciplinary Digital Publishing Institute (MDPI) )\u3001Crystals <\/em>(Switzerland; MDPI)\u3001Molbank\u00a0<\/em>(Switzerland; MDPI)\u3001Marine Drugs\u00a0<\/em>(Switzerland; MDPI)\u3001Biomolecules\u00a0<\/em>(Switzerland; Multidisciplinary Digital Publishing Institute (MDPI) )\u3002<\/p>\n

\u7814\u7a76\u8ad6\u6587<\/strong> (<\/strong>Research Papers<\/strong>)<\/strong>\uff1a
\n<\/strong>\u5305\u62ec (Include): \u7d50\u69cb\u5206\u6790 (Structural Analysis)\u3001\u53cd\u61c9\u6a5f\u5236\u63a2\u8a0e (Research on the Reaction Mechanism)\u3001\u85e5\u7269\u8a2d\u8a08\u5408\u6210 (Drug Design and Synthesis)\u3001\u6750\u6599\u79d1\u5b78 (Materials Science)\u3001\u4e2d\u91ab\u85e5\u5b78\u7814\u7a76 (Traditional Pharmaceutical Research)\u3001\u5065\u5eb7\u4fc3\u9032 (Health Promotion)\u3002<\/p>\n

\u5be9\u95b1\u8ad6\u6587<\/strong> (Referred Papers)<\/strong>\uff1a
\n<\/strong>Long-Chih Hwang<\/strong>*<\/span>, Shiun-Yau Yang, Chung-Lin Chuang and Gene-Hsiang Lee, \u201cAn Optimized Synthesis, Molecular Structure and Characterization of Benzylic Derivatives of 1,2,4-Triazin-3,5(2H<\/em>,4H<\/em>)-dione\u201d, Molecules<\/em>, 2017<\/strong>, 22<\/em>(11), 1924.
\n<\/strong><\/p>\n

G.H. Lee, L.C. Hwang<\/strong>*<\/span><\/strong>, \u201cCrystal Structure of 2-[(2-Acetoxyethoxy)methyl]-3-amino-1,2,4-triazin-5(2H<\/em>)-one\u201d, International Journal of Advanced Chemistry<\/em>, 2017<\/strong>, 5<\/em>(1), 35-38.<\/p>\n

Long-Chih Hwang*<\/u><\/strong>, Chung-Lin Chuang, and Gene-Hsiang Lee, \u201cPacking of Two Independent Molecules: 3-Amino-2-benzyl-6-bromo-1,2,4-triazin-5(2H<\/em>)-one\u201d, X-ray Structure Analysis Online<\/em>, 2016<\/strong>, 32<\/em>(7), 33-34.<\/p>\n

Hung-Chou Wu, Jean-Ho Chu, Chin-Wei, Li, Long-Chih Hwang<\/u><\/strong>, and Ming-Jung Wu*, \u201cPalladium-Catalyzed Regioselective Arylation of Pyrazolo[1,5-a<\/em>]pyridines via C-H Activation and Synthetic Applications on P38 Kinase Inhibitors”, Organometallics, 2016<\/strong>, 35<\/em>, 288-300.<\/p>\n

Hung-Chou Wu, Chia-Wen Yang, Long-Chih Hwang<\/u><\/strong>, and Ming-Jung Wu*, \u201cAu(I)-Catalyzed and Iodine-Mediated Cyclization of Enynylpyrazoles to Provide Pyrazolo[1,5-a<\/em>]pyridines\u201d, Organic & Biomolecular Chemistry<\/em>, 2012<\/strong>, 10<\/em>, 6640-6648.<\/p>\n

T.-P. Wang*, L.-L. Chang, S.-N. Chang, E.-C. Wang, L.-C. Hwang<\/u><\/strong>, Y.-H. Chen, and Y.-M. Wang, \u201cSuccessful Preparation and Characterization of Biotechnological Grade Agarose from Indigenous Gelidium amansii of Taiwan\u201d, Process Biochem.<\/em>, 2012<\/strong>, 47<\/em>, 550-554.<\/p>\n

Wang, Tzu-Pin*; Su, Yu-Chih; Chen, Yi; Liou, Yi-Ming; Lin, Kun-Liang; Wang, Eng-Chi; Hwang, Long-Chih<\/u><\/strong>; Wang, Yun-Ming; and Chen, Yen-hsu, “In vitro Selection and Characterization of a Novel Zn(II)-Dependent Phosphorothiolate Thiolesterase Ribozyme”, Biochemistry<\/em>, 2012<\/strong>, 51<\/em>, 496-510.<\/p>\n

Hung-Chou Wu, Long-Chih Hwang<\/u><\/strong>, and Ming-Jung Wu*, \u201cA copper-mediated cyclization reaction of hydrazine with enediynones providing pyrazolo[1,5-a<\/em>]pyridines\u201d, Organic & Biomolecular Chemistry<\/em>, 2011<\/strong>, 9<\/em>, 670-672.<\/p>\n

Long-Chih Hwang*<\/u><\/strong>, Yu-Chih Su, Tzu-Pin Wang, Li-The Liu, and Gene-Hsiang Lee, \u201cCrystal Structure of 3-Amino-2-benzyl-6-bromo-1,2,4-triazin-5(2H<\/em>)-one\u201d, X-ray Structure Analysis Online<\/em>, 2010<\/strong>, 26<\/em>(8), 61-62.<\/p>\n

Tzu-Pin Wang,* Yi-Jang Chiou, Yi Chen, Eng-Chi Wang, Long-Chih Hwang<\/u><\/strong>, Bing-Hung Chen, Yen-Hsu Chen, and Chun-Han Ko, \u201cVersatile Phosphoramidation Reactions for Nucleic Acid Conjugations with Peptides, Proteins, Chromophores, and Biotin Derivatives\u201d, Bioconjugate Chem.<\/em>, 2010<\/strong>, 21<\/em>, 1642-1655.<\/p>\n

Long-Chih Hwang*<\/u><\/strong>, Li-Teh Liu, Yu-Chih Su, and Gene-Hsiang Lee, \u201cCrystal Structure of 6-Bromo-1,2,4-triazin-3,5(2H<\/em>,4H<\/em>)-dione\u201d, Analytical Sciences<\/em>, 2008<\/strong>, 24<\/em>, x201-x202.<\/p>\n

T.H. Wei, C.W. Chen, L.C. Hwang<\/u><\/strong>, P.L. Tu, and T.C. Wen*, \u201cRoom temperature luminescence in CuI\/AgI quantum dots\u201d, J. of Luminescence<\/em>, 2008<\/strong>, 128<\/em>, 161-165.<\/p>\n

Hsiang-Wen Chen, Hung-Tien Kuo, Long-Chih Hwang<\/u><\/strong>, Mei-Fang Kuo, and Rei-Cheng Yang*, \u201cPROTEOMIC ALTERATION OF MITOCHONDRIAL ALDEHYDE DEHYDROGENASE 2 IN SEPSIS REGULATED BY HEAT SHOCK RESPONSE\u201d, SHOCK<\/em>, 2007<\/strong>, 28<\/em>, 710-716.<\/p>\n

L. C. Hwang<\/strong><\/span>, T. H. Wei, Y. L. Hsia, C. M. Li, P. L. Tu, and T.C. Wen*, \u201cPhotoluminescence of I-VII Semiconductor Compounds. Sensitized Luminescence from “Deep States” Recombination in CuBr\/AgBr Nanocrystals\u201d, J. Chin. Chem. Soc.<\/em>, 2006<\/strong>, 53<\/em>, 1235-1241.<\/p>\n

Yen-Hsiung Liao*, Long-Chih Hwang<\/u><\/strong>, Jing-Shwu Kao, Shuenn-Jiun Yiin, Shu-Fang Lin, Chia-Hong Lin, Yu-Cheng Lin, Tar-Ching Aw, \u201cLipid Peroxidation in Workers Exposed to Aluminium, Gallium, Indium, Arsenic, and Antimony in the Optoelectronic Industry\u201d, J. Occup. Environ. Med.<\/em>, 2006<\/strong>, 48<\/em>, 789-793.<\/p>\n

Long-Chih Hwang*<\/u><\/strong>, Chun-Hsien Tu, and Jung-Hui Wang, \u201cAromatization and Ring Cyclization: A Reasonable Understanding on the Ring Cyclization Mechanism of 3-Amino-6-hydrazino-1,2,4-triazin-5(2H<\/em>)-one Reacted with One-carbon Fragment Reagents or Nitrous Acid\u201d, J. Heterocyclic Chem<\/em>., 2006<\/strong>, 43<\/em>, 889-895.<\/p>\n

Long-Chih Hwang*<\/u><\/strong>, Shin-Yi Jane, Hsing-Yi Lai, Chun-Hsien Tu, and Gene-Hsiang Lee, \u201cSynthesis, Molecular Structure and Characterization of Allylic Derivatives of 6-Amino-3-methyl-1,2,4-triazolo[3,4-f<\/em>][1,2,4]triazin-8(7H<\/em>)-one\u201d, Molecules<\/em>, 2006<\/strong>, 11<\/em>, 444-452.<\/p>\n

T.H. Wei, T.C. Wen*, L.C. Hwang<\/u><\/strong>, S.C. Lee, W.Y. Chou, S.J. Hu, J.H. Wang, \u201cOptical nonlinearity and photoluminescence in CuI doped glass\u201d, Optical Materials<\/em>, 2006<\/strong>, 28<\/em>, 569-573.<\/p>\n

Long-Chih Hwang*<\/u><\/strong>, Chun-Hsien Tu, Jung-Hui Wang, and Gene-Hsiang Lee, \u201cSynthesis and Molecular Structure of 6-Amino-3-benzylmercapto-1,2,4-triazolo[3,4-f<\/em>][1,2,4]triazin- 8(7H<\/em>)-one\u201d, Molecules<\/em>, 2006<\/strong>, 11<\/em>, 169-176.<\/p>\n

Long-Chih Hwang*<\/u><\/strong>, Rang-Rong Wu, and Chun-Hsien Tu, \u201cAromatization and Ring Cyclization: A better understanding on the ring cyclization mechanism of 3-amino- 6-hydrazino-1,2,4-triazin-5-(2H<\/em>)-one reacted with acetic acid in N<\/em>,N<\/em>-dimethylformamide\u201d, Journal of Heterocyclic Chemistry<\/em>, 2005<\/strong>, 42<\/em>, 851-855.<\/p>\n

L.C. Hwang*<\/u><\/strong>, R.R. Wu, S.Y. Jane, and G.H. Lee, \u201cCrystal Structure of 3-Amino-1,2,4-triazine\u201d, Analytical Sciences<\/em>, 2003<\/strong>, 19<\/em>, x73-x74.<\/p>\n

L.C. Hwang<\/u><\/strong>, S.C. Lee, and T.C. Wen*, \u201cNonlinear absorption and refraction in lead glasses: enhanced by the small metal particle dispersion\u201d, Optic Communications<\/em>, 2003<\/strong>, 228<\/em>, 373-380.<\/p>\n

Yen-Hsiung Liao*, Long-Chih Hwang<\/u><\/strong>, Chih-Ching Chang, Yu-Jue Hong, I-Nong Lee, Jen-Hsuan Huang, Shu-Fang Lin, Maurice Shen, Chia-Hong Lin, Yung-Yen Gau, and Chin-Tzo Yang, \u201cBuilding Collapse and Human Deaths Resulting from the Chi-Chi Earthquake in Taiwan, September 1999\u201d, Archives of Environmental Health<\/em>, 2003<\/strong>, 58<\/em> (9), 572-578.<\/p>\n

T.C. Wen*, L.C. Hwang<\/u><\/strong>, W.Y. Lin, C.H. Chen, and C.H. Wu, \u201cNonlinear absorption of light: two-photon absorption and optical saturation in metalloporphyrin-doped boric acid glass\u201d, Chemical Physics<\/em>, 2003<\/strong>, 286<\/em>, 293-302.<\/p>\n

T.C. Wen*, L.C. Hwang<\/u><\/strong>, and W.Y. Lin, \u201cNonlinear Light Absorption in Porphyrin Derivatives Including the Complexes of the IIIa Metal Group\u201d, Journal of Chinese Chemical Society<\/em>, 2002<\/strong>, 49<\/em>, 875-881.<\/p>\n

L.C. Hwang*<\/u><\/strong>, Chun-Hsien Tu, Jung-Hui Wang, Gene-Hsiang Lee, and Yu Wang, \u201cCrystal Structure of 6-Amino-3-ethyl-1,2,4-triazolo[3,4-f<\/em>][1,2,4]triazin- 8(7H<\/em>)-one\u201d, Analytical Sciences<\/em>, 2002<\/strong>, 18<\/em>, 853-854.<\/p>\n

L.C. Hwang*<\/u><\/strong>, Jung-Hui Wang, Cherng-Chyi Tzeng, Gene-Hsiang Lee, and Shie-Ming Peng, \u201cCrystal Structure of 3-Amino-1,2,4-triazin-5(2H<\/em>)-one\u201d, Analytical Sciences<\/em>, 2002<\/strong>, 18<\/em>, 723-724.<\/p>\n

L.C. Hwang<\/u><\/strong>, C.Y. Tsai, C.J. Tiao, and T.C. Wen*, \u201cOptic Nonlinearities of a Copper Complex of Pyrazinoporphyrazine\u201d, Optical and Quantum Electronics<\/em>, 2000<\/strong>, 32<\/em>, 641-656.<\/p>\n

C.J. Tiao, L.C. Hwang<\/u><\/strong>, and T.C. Wen*, \u201cTwo-Photon Absorption and Excited-State Refractions in Anthraquinone Dyes\u201d, J. Chin. Chem. Soc<\/em>., 1998<\/strong>, 45<\/em>, 659-665.<\/p>\n

T.C. Wen*, C.J. Tiao, L.C. Hwang<\/u><\/strong>, and C.Y. Tsai, \u201cSynthesis and Third-Order Nonlinear Optical Properties of Liner p-Acenequinones\u201d, Synthetic Metals<\/em>, 1998<\/strong>, 92<\/em>, 235-243.<\/p>\n

T.C. Wen*, S.J. Jen, H.W. Liu, L.C. Hwang<\/u><\/strong>, and I.D. Lian, \u201cOptical Nonlinearities of Phthalocyanines and Naphthalocyanines\u201d, J. Chin. Chem. Soc<\/em>., 1996<\/strong>, 43<\/em>, 123-132.<\/p>\n

C.C. Tzeng*, L.C. Hwang<\/u><\/strong>, C.C. Chen, and D.C. Wei, \u201cSynthesis of Racemic 5-Substituted 1-(2,3-Dihydroxypropyl)-5-substituted-6-azauracils and Their Isosterric Isomers\u201d, Nucleosides & Nucleotides<\/em>, 1995<\/strong>, 14<\/em>, 1425-1435.<\/p>\n

L.C. Hwang<\/u><\/strong>, C.J. Wang, G.H. Lee, Y. Wang, and C.C. Tzeng*, \u201cSynthesis and Structure Assignment of 1-[(2-Hydroxy-ethoxy)methyl]- and 1-[(1,3-Dihydroxy- 2-propoxy)methyl]- 6-azaisocytosine\u201d, Heterocycles<\/em>, 1995<\/strong>, 41<\/em>, 293-301.<\/p>\n

L.C. Hwang<\/u><\/strong>, E.C. Wang, K.H. Lee, and C.C. Tzeng*, \u201cSynthetic and Antiviral Studies on Certain Acyclonucleosides of 5-Substituted-6-azauracils\u201d, Chin. Pharm. J.<\/em>, 1995<\/strong>, 47<\/em>, 1-11.<\/p>\n

L.C. Hwang<\/u><\/strong>, D.C. Wei, M.C. Cheng, Y. Wang, and C.C. Tzeng*, \u201cSynthesis and Structure Assignment of 1-(2-Acetoxyethoxy)methyl Derivatives of 5-Chloro-6-azauracil and 5-Bromo-6-azaisocytosine\u201d, Nucleosides & Nucleotides<\/em>, 1995<\/strong>, 13<\/em>, 2185-2193.<\/p>\n

D.C. Wei, L.C. Hwang<\/u><\/strong>, and C.C. Tzeng*, \u201cCondensed as<\/em>-Triazine: Synthesis of Imidazo[4,5-e<\/em>]-as<\/em>-triazine 1-Oxides (6-Azapurine 6-Oxides) as Guanine and Hypoxanthine Analogues\u201d, Heterocycles<\/em>, 1994<\/strong>, 38<\/em>, 2009-2015.<\/p>\n

C.C. Tzeng*, D.C. Wei, L.C. Hwang<\/u><\/strong>, M.C. Cheng, and Y. Wang, \u201cCondensed 1,2,4-Triazines: Synthesis of 5-Benzyl-5H<\/em>-imidazo[4,5-e<\/em>]1,2,4-triazine 1-Oxides (9-Benzyl-6-azapurine 6-Oxides)\u201d, J. Chem. Soc. Perkin Trans<\/em>., 1994<\/strong>, 1<\/em>, 2253-2256.<\/p>\n

L.C. Hwang<\/u><\/strong>, D.C. Wei, C.H. Han, K.H. Lee, and C.C. Tzeng*, \u201cCondensed as-Triazines. Part 4. Synthesis of 2-Amino-9-benzyl-6-azapurine (3-Amino-5-benzyl-5H-imidazo[4,5-e<\/em>]- as<\/em>-triazine)\u201d, J. Chem. Research<\/em> (S), 1994<\/strong>, 121.; J. Chem. Research <\/em>(M), 1994<\/strong>, 0831-0842.<\/p>\n

D.C. Wei, L.C. Hwang<\/u><\/strong>, C.H. Han, K.H. Lee, and C.C. Tzeng*, \u201cCondensed as-Triazine III: Synthesis of 2-Amino-6-azapurine (3-Aminoimidazo[4,5-e<\/em>]- as<\/em>-triazine) as a Potential Antitumor Agent\u201d, Heterocycles<\/em>, 1993<\/strong>, 36<\/em>, 2733-2743.<\/p>\n","protected":false},"excerpt":{"rendered":"

\u7814\u7a76\u8208\u8da3 (Research Interests)\uff1a (1)\u7d50\u69cb\u5206\u6790\u8207\u53cd\u61c9\u6a5f\u5236\u63a2 … \u95b1\u8b80\u5168\u6587 →<\/span><\/a><\/p>\n","protected":false},"author":35,"featured_media":0,"parent":0,"menu_order":2,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_exactmetrics_skip_tracking":false,"_exactmetrics_sitenote_active":false,"_exactmetrics_sitenote_note":"","_exactmetrics_sitenote_category":0,"footnotes":""},"class_list":["post-41","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/wp.kmu.edu.tw\/lnchhw\/wp-json\/wp\/v2\/pages\/41","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/wp.kmu.edu.tw\/lnchhw\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/wp.kmu.edu.tw\/lnchhw\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/wp.kmu.edu.tw\/lnchhw\/wp-json\/wp\/v2\/users\/35"}],"replies":[{"embeddable":true,"href":"https:\/\/wp.kmu.edu.tw\/lnchhw\/wp-json\/wp\/v2\/comments?post=41"}],"version-history":[{"count":17,"href":"https:\/\/wp.kmu.edu.tw\/lnchhw\/wp-json\/wp\/v2\/pages\/41\/revisions"}],"predecessor-version":[{"id":64,"href":"https:\/\/wp.kmu.edu.tw\/lnchhw\/wp-json\/wp\/v2\/pages\/41\/revisions\/64"}],"wp:attachment":[{"href":"https:\/\/wp.kmu.edu.tw\/lnchhw\/wp-json\/wp\/v2\/media?parent=41"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}