{"id":2340,"date":"2014-03-03T17:47:02","date_gmt":"2014-03-03T09:47:02","guid":{"rendered":"http:\/\/wp.kmu.edu.tw\/rd\/?p=2340"},"modified":"2014-03-05T17:16:13","modified_gmt":"2014-03-05T09:16:13","slug":"%e7%a0%94%e7%a9%b6%e6%96%b0%e7%9f%a5-16","status":"publish","type":"post","link":"https:\/\/wp.kmu.edu.tw\/rd\/archives\/2340","title":{"rendered":"\u7814\u7a76\u65b0\u77e5"},"content":{"rendered":"<p style=\"text-align: right\"><a style=\"font-style: normal;text-align: right\" href=\"http:\/\/wp.kmu.edu.tw\/rd\/archives\/2338\">\u56de\u7b2c0018\u671f\u4e3b\u9801<\/a><\/p>\n<h1><span style=\"font-size: x-large;color: #c10000\">\u4e00\u3001\u7814\u7a76\u65b0\u77e5<\/span><\/h1>\n<h1><span style=\"color: #0000ff\"><a name=\"ResNew1\"><\/a><span style=\"color: #0000ff\">Rejuvenation of the <strong>muscle st<\/strong>em cell population restores strength to injured aged muscles<\/span><\/span><\/h1>\n<p>Nature Medicine (advance online publication) Cosgrove BD, Gilbert PM, Porpiglia E, Mourkioti F, Lee SP, Corbel SY, Llewellyn ME, Delp S, Blau HM\uff08\u611f\u8b1d\u9ad8\u96c4\u91ab\u5b78\u5927\u5b78\u76ae\u819a\u5b78\u79d1 \u85cd\u653f\u54f2\u6559\u6388 \u6458\u8b6f\uff09<\/p>\n<p>\u8001\u5e74\u4eba\u7684\u808c\u8089\u5e38\u6709\u7121\u529b\u548c\u518d\u751f\u56f0\u96e3\u7684\u554f\u984c\u3002\u4e00\u822c\u8a8d\u70ba\u808c\u8089\u5e79\u7d30\u80de(muscle stem cells, MuSCs)\u7684\u529f\u80fd\u7f3a\u5931\u4e3b\u8981\u662f\u5916\u90e8\u74b0\u5883\u56e0\u7d20\u6240\u9020\u6210\uff0c\u800c\u5e79\u7d30\u80de\u672c\u8eab\u4e26\u4e0d\u6703\u56e0\u8870\u8001\u800c\u7522\u751f\u8b8a\u5316\u3002\u7136\u800c\uff0c\u6b64\u8ad6\u6587\u7814\u7a76\u767c\u73fe\u8ca0\u8cac\u4fee\u5fa9\u640d\u50b7\u7684\u808c\u8089\u5e79\u7d30\u80de\u6703\u96a8\u8457\u6642\u9593\u800c\u9010\u6f38\u8001\u5316\uff0c\u5176\u672c\u8eab\u751f\u6210\u65b0\u808c\u8089\u7e96\u7dad\u7684\u80fd\u529b\u4ea6\u96a8\u6642\u9593\u9010\u6f38\u840e\u7e2e\uff0c\u5373\u4f7f\u79fb\u690d\u8001\u5e74\u5c0f\u9f20\u7684\u808c\u8089\u5e79\u7d30\u80de\u81f3\u5e74\u8f15\u5c0f\u9f20\u9ad4\u5167\u4e5f\u7121\u6cd5\u6539\u8b8a\u8001\u5e74\u5c0f\u9f20\u808c\u8089\u5e79\u7d30\u80de\u529f\u80fd\u7f3a\u5931\u7684\u73fe\u8c61\u3002\u4e3b\u8981\u662f\u56e0\u70bap38\u03b1\u7684\u548cp38\u03b2 MAP\u6fc0\u9176\u9014\u5f91\u7684\u6d3b\u6027\u5347\u9ad8\uff0c\u4f7f\u808c\u8089\u5e79\u7d30\u80de\u8001\u5316\uff0c\u9020\u6210\u7d30\u80de\u529f\u80fd\u8870\u9000\u3002\u4f5c\u8005\u5c07\u5e74\u8001\u5c0f\u9f20\u808c\u8089\u5e79\u7d30\u80de\u57f9\u990a\u5728\u6c34\u51dd\u81a0\u4e2d\uff0c\u4e26\u4f7f\u7528\u85e5\u7269\u963b\u65b7\u5e74\u8001\u5c0f\u9f20\u808c\u8089\u5e79\u7d30\u80de\u4e2d\u7684p38 MAP\u6fc0\u9176\u9014\u5f91\uff0c\u57f9\u990a\u51fa\u5927\u91cf\u6709\u6d3b\u529b\u4e14\u80fd\u5920\u4fee\u5fa9\u808c\u8089\u640d\u50b7\u7684\u5e79\u7d30\u80de\u3002\u5be6\u9a57\u8b49\u5be6\u7d93\u904e\u8655\u7406\u7684\u5e74\u8001\u5c0f\u9f20\u808c\u8089\u5e79\u7d30\u80de\u80fd\u5920\u4fee\u5fa9\u808c\u8089\u640d\u50b7\u4e26\u6062\u5fa9\u5c0f\u9f20\u53d7\u640d\u808c\u8089\u7684\u5f37\u5ea6\u3002\u9019\u500b\u7814\u7a76\u70ba\u8001\u5e74\u75c5\u60a3\u63d0\u4f9b\u4e86\u4e00\u500b\u7bc4\u4f8b\uff0c\u6216\u8a31\u672a\u4f86\u80fd\u4ee5\u57f9\u990a\u81ea\u9ad4\u808c\u8089\u5e79\u7d30\u80de\u7684\u65b9\u5f0f\u6cbb\u7642\u808c\u8089\u640d\u50b7\uff0c\u4e26\u8aaa\u660e\u4e86\u751f\u7269\u7269\u7406\u548c\u751f\u7269\u5316\u5b78\u4e4b\u9593\u5c0d\u5e79\u7d30\u80de\u8abf\u63a7\u7684\u5354\u540c\u4f5c\u7528\u3002<\/p>\n<p style=\"text-align: right\"><a href=\"http:\/\/wp.kmu.edu.tw\/rd\/archives\/2338\">\u56de\u7b2c0018\u671f\u4e3b\u9801<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u56de\u7b2c0018\u671f\u4e3b\u9801 \u4e00\u3001\u7814\u7a76\u65b0\u77e5 Rejuvenation of the mus &hellip; <a href=\"https:\/\/wp.kmu.edu.tw\/rd\/archives\/2340\">\u95b1\u8b80\u5168\u6587 <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_exactmetrics_skip_tracking":false,"_exactmetrics_sitenote_active":false,"_exactmetrics_sitenote_note":"","_exactmetrics_sitenote_category":0,"footnotes":""},"categories":[26],"tags":[],"class_list":["post-2340","post","type-post","status-publish","format-standard","hentry","category-26"],"_links":{"self":[{"href":"https:\/\/wp.kmu.edu.tw\/rd\/wp-json\/wp\/v2\/posts\/2340","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/wp.kmu.edu.tw\/rd\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/wp.kmu.edu.tw\/rd\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/wp.kmu.edu.tw\/rd\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/wp.kmu.edu.tw\/rd\/wp-json\/wp\/v2\/comments?post=2340"}],"version-history":[{"count":18,"href":"https:\/\/wp.kmu.edu.tw\/rd\/wp-json\/wp\/v2\/posts\/2340\/revisions"}],"predecessor-version":[{"id":2433,"href":"https:\/\/wp.kmu.edu.tw\/rd\/wp-json\/wp\/v2\/posts\/2340\/revisions\/2433"}],"wp:attachment":[{"href":"https:\/\/wp.kmu.edu.tw\/rd\/wp-json\/wp\/v2\/media?parent=2340"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/wp.kmu.edu.tw\/rd\/wp-json\/wp\/v2\/categories?post=2340"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/wp.kmu.edu.tw\/rd\/wp-json\/wp\/v2\/tags?post=2340"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}