{"id":2597,"date":"2014-05-28T09:41:00","date_gmt":"2014-05-28T01:41:00","guid":{"rendered":"http:\/\/wp.kmu.edu.tw\/rd\/?p=2597"},"modified":"2014-06-05T14:50:04","modified_gmt":"2014-06-05T06:50:04","slug":"%e8%ab%96%e6%96%87%e7%a0%94%e7%a9%b6%e8%88%87%e5%88%86%e4%ba%ab-13","status":"publish","type":"post","link":"https:\/\/wp.kmu.edu.tw\/rd\/archives\/2597","title":{"rendered":"\u8ad6\u6587\u7814\u7a76\u8207\u5206\u4eab"},"content":{"rendered":"<p style=\"text-align: right\"><a href=\"http:\/\/wp.kmu.edu.tw\/rd\/archives\/2593\">\u56de\u7b2c0021\u671f\u4e3b\u9801<\/a><\/p>\n<h1><span style=\"font-size: x-large;color: #c10000\">\u4e8c\u3001\u8ad6\u6587\u8207\u7814\u7a76\u5206\u4eab<\/span><\/h1>\n<p><a name=\"PaperRes1\"><\/a><\/p>\n<h1><span style=\"color: #0000ff\">\uff08\u4e00\uff09\u8ad6\u6587<\/span><\/h1>\n<ul>\n<li><span style=\"color: #3366ff\">\u984c\u76ee\uff1a<strong><br \/>\nThe role of chemoprevention by selective cyclooxygenase-2 inhibitors in colorectal cancer patients &#8211; a population-based study.<br \/>\n\uff08\u9ad8\u96c4\u91ab\u5b78\u5927\u5b78\u85e5\u5b78\u7cfb\u694a\u5955\u99a8\u6559\u6388\u63d0\u4f9b\uff09<\/strong><\/span><\/li>\n<\/ul>\n<ul>\n<li>\u4f5c\u8005\uff1a Yang YH, Yang Kao YH, Cheng CL, Ho PS, Ko YC. BMC Cancer 2012; 12: 582.<\/li>\n<\/ul>\n<ul>\n<li>\u63a2\u8a0e\u9078\u64c7\u6027\u7b2c\u4e8c\u578b\u74b0\u6c27\u9176\u6291\u5236\u5291\u5c0d\u65bc\u5927\u8178\u76f4\u8178\u764c\u7684\u5316\u5b78\u9810\u9632\u6548\u679c\u4e4b\u5927\u578b\u4eba\u53e3\u57fa\u790e\u7684\u7814\u7a76\u76ee\u524d\u4ecd\u6709\u9650\uff0c\u672c\u7814\u7a76\u4e4b\u4e3b\u8981\u76ee\u7684\u662f\u91dd\u5c0d\u9078\u64c7\u6027\u7b2c\u4e8c\u578b\u74b0\u6c27\u9176\u6291\u5236\u5291\u5728\u4e0d\u540c\u7684\u85e5\u54c1\u6301\u6709\u7387\uff0c\u8a55\u4f30\u5176\u5316\u5b78\u9810\u9632\u7684\u8da8\u52e2\u53ca\u5291\u91cf\u6548\u61c9\u3002\u7814\u7a76\u65b9\u6cd5\u4ee5\u53f0\u7063\u5168\u6c11\u5065\u4fdd\u7814\u7a76\u8cc7\u6599\u5eab\u9032\u884c\u4e00\u4eba\u53e3\u5b78\u57fa\u790e\u7684\u75c5\u4f8b\u5c0d\u7167\u7814\u7a76\u3002\u7814\u7a76\u6a23\u672c\u5171\u670921,460\u4f4d\u5927\u8178\u76f4\u8178\u764c\u60a3\u8005\u53ca79,331\u4f4d\u5c0d\u7167\u8005\u3002\u7d71\u8a08\u5206\u6790\u63a1\u7528\u689d\u4ef6\u5f0f\u5c0d\u6578\u8ff4\u6b78\u8a08\u7b97\u4f7f\u7528\u9078\u64c7\u6027\u7b2c\u4e8c\u578b\u74b0\u6c27\u9176\u6291\u5236\u5291\u5728\u4e0d\u540c\u6642\u9593\u6307\u6a19\u65e5\u671f\u524d\u7684\u6642\u9593\u9577\u5ea6(5\u5e74\u30013\u5e74\u30011\u5e74\u30016\u500b\u6708\u30013\u500b\u6708)\u4e4b\u98a8\u96aa\u6bd4\u3002\u7814\u7a76\u7d50\u679c\u986f\u793a\uff0c\u4f7f\u7528\u9078\u64c7\u6027\u7b2c\u4e8c\u578b\u74b0\u6c27\u9176\u6291\u5236\u5291\u4e4b\u60a3\u8005\uff0c\u91dd\u5c0d\u7f79\u60a3\u5927\u8178\u76f4\u8178\u764c\u65b9\u9762\uff0c\u51765\u5e74\u7d2f\u7a4d\u4f7f\u7528\u91cf\u67090.51 (95\u4fe1\u8cf4\u5340\u95930.29~0.90\uff0cp\u503c=0.021)\u7684\u98a8\u96aa\u6bd4\u3002\u57285\u5e74\u30013\u5e74\u53ca1\u5e74\u768410%\u4ee5\u4e0a\u6301\u6709\u7387\u90fd\u6709\u986f\u793a\u8f03\u4f4e\u7684\u98a8\u96aa\uff1b\u5176\u4e2d\uff0c\u6700\u65e9\u52306\u500b\u6708\u7684\u4f7f\u7528\u820a\u6709\u5448\u73fe\u7d71\u8a08\u4e0a\u986f\u8457\u5dee\u7570\u3002\u7d50\u8ad6\uff1a\u6211\u5011\u7684\u7d50\u679c\u986f\u793a\u9078\u64c7\u6027\u7b2c\u4e8c\u578b\u74b0\u6c27\u9176\u6291\u5236\u529110%\u4ee5\u4e0a\u4e4b\u85e5\u54c1\u6301\u6709\u7387\uff0c\u53ef\u80fd\u6703\u964d\u4f4e\u7f79\u60a3\u5927\u8178\u76f4\u8178\u764c\u7684\u98a8\u96aa\u3002\u7531\u65bc\u76ee\u524d\u76f8\u95dc\u7684\u5927\u578b\u4eba\u53e3\u5b78\u57fa\u790e\u4e4b\u7814\u7a76\u6709\u9650\uff0c\u56e0\u6b64\u672c\u7814\u7a76\u7684\u767c\u73fe\u53ef\u4ee5\u8ca2\u737b\u5728\u9078\u64c7\u6027\u7b2c\u4e8c\u578b\u74b0\u6c27\u9176\u6291\u5236\u5291\u4e4b\u61c9\u7528\u65bc\u6c92\u6709\u5927\u8178\u76f4\u8178\u764c\u660e\u986f\u98a8\u96aa\u60a3\u8005\u7684\u5316\u5b78\u9810\u9632\u6548\u679c\u3002<\/li>\n<\/ul>\n<p><a name=\"PaperRes2\"><\/a><\/p>\n<ul>\n<li><span style=\"color: #3366ff\">\u984c\u76ee\uff1a<strong><br \/>\nIron-Catalyzed Oxidative Direct alpha-C-H Bond Functionalization of Cyclic Ethers: Selective C-O Bond Formation in the Presence of a Labile Aldehyde Group.<br \/>\n\uff08\u9ad8\u96c4\u91ab\u5b78\u5927\u5b78\u5f35\u82b3\u69ae\u6559\u6388\u63d0\u4f9b\u6458\u8981\uff09<\/strong><\/span><\/li>\n<\/ul>\n<ul>\n<li>\u4f5c\u8005\uff1a Barve, Balaji D.; Wu, Yang-Chang; El-Shazly, Mohamed; Korinek, Michal; Cheng, Yuan-Bin; Wang, Jeh-Jeng; Chang, Fang-Rong  ORGANIC LETTERS v.16 n.7 p.1912-1915<\/li>\n<\/ul>\n<ul>\n<li>ABSTRACT: Iron catalyzed oxidative coupling of salicylaldehydes with cyclic ethers proceeded through the direct \u03b1-C\u2212H functionalization of ethers, forming the corresponding acetals in moderate to excellent yields. This is the first example of iron catalyzed selective C\u2212O bond formation in the presence of a sensitive aldehyde moiety.<br \/>\n\u5229\u7528\u9435\u50ac\u5316\u65bc\u6c34\u694a\u919b\u8207\u74b0\u919a\u53cd\u61c9\u9032\u884c\u919a\u985e\u7684\u03b1-C-H\u5b98\u80fd\u57fa\u4fee\u98fe\uff0c\u9ad8\u6548\u7387\u5730\u5f62\u6210\u7e2e\u919b\u884d\u751f\u7269\u3002\u4e14\u7b2c\u4e00\u500b\u767c\u8868\u85c9\u7531\u9435\u50ac\u5316\u65bc\u5177\u9ad8\u6d3b\u6027\u7684\u919b\u57fa\u7d50\u69cb\u4e0a\u9078\u64c7\u6027\u5f62\u6210C\u2212O\u9375\u7d50\u4e4b\u7814\u7a76\u3002\n<\/li>\n<\/ul>\n<p style=\"text-align: right\"><a href=\"http:\/\/wp.kmu.edu.tw\/rd\/archives\/2593\">\u56de\u7b2c0021\u671f\u4e3b\u9801<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u56de\u7b2c0021\u671f\u4e3b\u9801 \u4e8c\u3001\u8ad6\u6587\u8207\u7814\u7a76\u5206\u4eab \uff08\u4e00\uff09\u8ad6\u6587 \u984c\u76ee\uff1a The role o &hellip; <a href=\"https:\/\/wp.kmu.edu.tw\/rd\/archives\/2597\">\u95b1\u8b80\u5168\u6587 <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_exactmetrics_skip_tracking":false,"_exactmetrics_sitenote_active":false,"_exactmetrics_sitenote_note":"","_exactmetrics_sitenote_category":0,"footnotes":""},"categories":[29],"tags":[],"class_list":["post-2597","post","type-post","status-publish","format-standard","hentry","category-29"],"_links":{"self":[{"href":"https:\/\/wp.kmu.edu.tw\/rd\/wp-json\/wp\/v2\/posts\/2597","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/wp.kmu.edu.tw\/rd\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/wp.kmu.edu.tw\/rd\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/wp.kmu.edu.tw\/rd\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/wp.kmu.edu.tw\/rd\/wp-json\/wp\/v2\/comments?post=2597"}],"version-history":[{"count":3,"href":"https:\/\/wp.kmu.edu.tw\/rd\/wp-json\/wp\/v2\/posts\/2597\/revisions"}],"predecessor-version":[{"id":2620,"href":"https:\/\/wp.kmu.edu.tw\/rd\/wp-json\/wp\/v2\/posts\/2597\/revisions\/2620"}],"wp:attachment":[{"href":"https:\/\/wp.kmu.edu.tw\/rd\/wp-json\/wp\/v2\/media?parent=2597"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/wp.kmu.edu.tw\/rd\/wp-json\/wp\/v2\/categories?post=2597"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/wp.kmu.edu.tw\/rd\/wp-json\/wp\/v2\/tags?post=2597"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}