{"id":17,"date":"2016-10-27T22:21:02","date_gmt":"2016-10-27T14:21:02","guid":{"rendered":"http:\/\/wp.kmu.edu.tw\/shioulan\/?page_id=17"},"modified":"2025-06-23T11:18:59","modified_gmt":"2025-06-23T03:18:59","slug":"cv","status":"publish","type":"page","link":"https:\/\/wp.kmu.edu.tw\/shioulan\/","title":{"rendered":"CV"},"content":{"rendered":"<p style=\"text-align: left\"><strong>\u9673<\/strong> <strong>\u79c0<\/strong> <strong>\u862d<\/strong>\u00a0 <strong>\u00a0\u6559 \u6388 <\/strong>(Professsor, Shiou-Lan Chen)<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"\" src=\"http:\/\/wp.kmu.edu.tw\/shioulan\/files\/2022\/01\/0918380641.2-scaled.jpg\" width=\"258\" height=\"218\" \/><\/p>\n<ul>\n<li style=\"text-align: left\">\u570b\u9632\u91ab\u5b78\u9662 \u91ab\u5b78\u79d1\u5b78\u7814\u7a76\u6240\u00a0 \u535a \u58eb (PhD)<\/li>\n<li>\u570b\u9632\u91ab\u5b78\u9662 \u85e5\u7406\u5b78\u7814\u7a76\u6240 \u78a9\u58eb<\/li>\n<li>\u570b\u9632\u91ab\u5b78\u9662 \u8b77\u7406\u5b78\u7cfb \u5b78\u58eb<\/li>\n<li style=\"text-align: left\">Tel: :+886-7-3121101 ext\u00a05092 ext 434<\/li>\n<li style=\"text-align: left\">E-mail: shioulan@kmu.edu.tw<strong><u><br \/>\n<\/u><\/strong><\/li>\n<\/ul>\n<p><strong><u><strong><u><strong><u>Current position (\u73fe\u4efb\u8077\u4f4d):<\/u><\/strong><\/u><\/strong><\/u><\/strong><\/p>\n<ul>\n<li>Section Chief of Curriculum, College of Medicine, Kaohsiung Medical University (KMU), Taiwan (\u6559\u5b78\u7d44\u7d44\u9577,\u00a0 \u9ad8\u96c4\u91ab\u5b78\u5927\u5b78, \u91ab\u5b78\u9662)<\/li>\n<li>Professor, Graduate Institute of Medicine,\u00a0 KMU, Taiwan (\u6559\u6388,\u00a0 \u9ad8\u96c4\u91ab\u5b78\u5927\u5b78, \u91ab\u5b78\u9662, \u91ab\u5b78\u7814\u7a76\u6240)<\/li>\n<li>Jointly Appointed Professor, MSc Program in Tropical Medicine, KMU, Taiwan \u00a0(\u5408\u8058\u6559\u6388,\u00a0 \u9ad8\u96c4\u91ab\u5b78\u5927\u5b78, \u91ab\u5b78\u9662, \u71b1\u5e36\u91ab\u5b78\u7814\u7a76\u6240)<\/li>\n<li>Jointly Appointed Researcher, Department of Medicine Research, KMU Hospital (\u5408\u8058\u7814\u7a76\u54e1,\u00a0 \u9ad8\u96c4\u91ab\u5b78\u5927\u5b78\u9644\u8a2d\u91ab\u9662, \u81e8\u5e8a\u91ab\u5b78\u7814\u7a76\u90e8)<\/li>\n<\/ul>\n<p><strong><u><strong><u>Experiences (\u7d93\u6b77):<\/u><\/strong><\/u><\/strong><\/p>\n<ul>\n<li>Associate Professor, Department of Neurology, KMU, Taiwan (\u526f\u6559\u6388,\u00a0 \u00a0\u9ad8\u96c4\u91ab\u5b78\u5927\u5b78, \u91ab\u5b78\u9662, \u91ab\u5b78\u7814\u7a76\u6240)<\/li>\n<li>Assistant Professor, Department of Neurology, KMU, Taiwan (\u52a9\u7406\u6559\u6388,\u00a0 \u00a0\u9ad8\u96c4\u91ab\u5b78\u5927\u5b78, \u91ab\u5b78\u9662, \u91ab\u5b78\u7cfb, \u795e\u7d93\u5b78\u79d1)<\/li>\n<li>Assistant Professor, Department of Psychiatry, National Cheng Kung University, Taiwan (\u52a9\u7406\u6559\u6388,\u00a0 \u00a0\u570b\u7acb\u6210\u529f\u5927\u5b78, \u91ab\u5b78\u9662, \u7cbe\u795e\u5b78\u79d1)<\/li>\n<li>Visiting Scholar, Institute of Pharmacology, University of Minnesota, USA\u00a0 (\u8a2a\u554f\u5b78\u8005\u00a0 \u00a0\u7f8e\u570b\u660e\u5c3c\u8607\u9054\u5927\u5b78, \u85e5\u7406\u5b78\u6240)<\/li>\n<li>Armed Forces Taoyuan General Hospital\/Assistant Head Nurse (\u570b\u8ecd\u6843\u5712\u7e3d\u91ab\u9662 \u526f\u8b77\u7406\u9577)<\/li>\n<li>Air Force General Hospital Nurse\/Aeromedical Nurse (\u7a7a\u8ecd\u7e3d\u91ab\u9662 \u8b77\u7406\u5e2b\/\u822a\u7a7a\u8b77\u7406\u5e2b)<\/li>\n<\/ul>\n<p><strong><u>Research fields (\u7814\u7a76\u9818\u57df):<\/u><\/strong><strong>\u00a0<\/strong><\/p>\n<ul>\n<li>\u75bc\u75db\u63a7\u5236 (pain control)<\/li>\n<li>\u85e5\u7269\u6210\u766e (substance abuse)<\/li>\n<li>\u795e\u7d93\u9000\u5316\u6027\u75be\u75c5 (neuronal degenerative diseases)<\/li>\n<\/ul>\n<p><span style=\"text-decoration: underline;color: #800080\"><strong>\u6b61\u8fce\u52a0\u5165\u6211\u5011\u7684\u806f\u5408\u795e\u7d93\u79d1\u5b78\u5be6\u9a57\u5ba4 !<\/strong><\/span><\/p>\n<div id=\"attachment_197\" style=\"width: 604px\" class=\"wp-caption alignnone\"><a href=\"http:\/\/wp.kmu.edu.tw\/shioulan\/files\/2023\/04\/IMG_8170-scaled.jpg\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-197\" class=\"wp-image-197\" src=\"http:\/\/wp.kmu.edu.tw\/shioulan\/files\/2023\/04\/IMG_8170-300x225.jpg\" alt=\"\" width=\"594\" height=\"446\" srcset=\"https:\/\/wp.kmu.edu.tw\/shioulan\/files\/2023\/04\/IMG_8170-300x225.jpg 300w, https:\/\/wp.kmu.edu.tw\/shioulan\/files\/2023\/04\/IMG_8170-1024x769.jpg 1024w, https:\/\/wp.kmu.edu.tw\/shioulan\/files\/2023\/04\/IMG_8170-768x577.jpg 768w, https:\/\/wp.kmu.edu.tw\/shioulan\/files\/2023\/04\/IMG_8170-1536x1153.jpg 1536w, https:\/\/wp.kmu.edu.tw\/shioulan\/files\/2023\/04\/IMG_8170-2048x1538.jpg 2048w\" sizes=\"auto, (max-width: 594px) 100vw, 594px\" \/><\/a><p id=\"caption-attachment-197\" class=\"wp-caption-text\">2023 \u5be6\u9a57\u5ba4\u805a\u9910<\/p><\/div>\n<p style=\"text-align: left\"><strong><u>\u4ee3\u8868\u8457\u4f5c (Representive publications)<u>: <\/u><\/u><\/strong>\u00a0Total publications: 105 (SCI)\uff0cH-index: 21<\/p>\n<ol>\n<li>Liu YC, Chiu BY, Tu KY, Liu IC,\u00a0<strong><u>Chen SL*<\/u>.<\/strong> Intermittent Hypoxia Triggers Glial Cell Activation, GluN2B Receptor Upregulation and Hyperalgesia in a Mouse Model of Sleep Apnea. European J of Pain (SCI).\u00a0<strong>2025<\/strong> Jul;29(6):e70039.<\/li>\n<li>Chu CH, Chang YC, Liu KT, Liu YC, Chou MC, Liu CK, Chen CH, Chang JL,\u00a0<strong><u>Chen SL*<\/u><\/strong>. Intermittent Hypoxia Damages Tyrosine Hydroxylase-Containing Neurons in the Substantia Nigra and Locus Coeruleus but Not Hippocampal Neurons in Male Mouse Models of Early-Stage Sleep Apnea. J Neuroscience Research (SCI).\u00a0<strong>2025<\/strong> Jun;103(6):e70050.<\/li>\n<li>Chou MC\u2020, Lee HC\u2020, Liu YC, Yen P SY, Liu CK, Chen CH, Hsieh TH, and <strong><u>Chen SL*<\/u><\/strong>. Long-term High-fat Diet Consumption Depletes Glial Cells and Tyrosine Hydroxylase\u2013containing Neurons in the Brain of Middle-aged Rats. <strong>2022, <\/strong>Cells, 11, 295 (IF: 7.6).<\/li>\n<li>Liu YC, Hsiao HT, Wang J CF, Wen TC, <strong><u>Chen SL*<\/u><\/strong>. TGF-\u03b21 in plasma and cerebrospinal fluid can be used as a biological indicator of chronic pain in patients with osteoarthritis. <strong>2022, <\/strong>PLOS ONE, Jan, doi.org\/10.1371\/journal.pone.0262074 (IF:3.24, ranking: 26\/72).<\/li>\n<li>Fan Y\u2020,\u00a0Chou MC\u2020,\u00a0Liu YC,\u00a0Liu CK,\u00a0Chen CH, <strong><u>Chen SL*.<\/u><\/strong>\u00a0 Intermittent Hypoxia Activates N-Methyl-D Aspartate Receptors to Induce Anxiety Behaviors in a Mouse Model of Sleep Associated Apnea. <strong>2021<\/strong>, Molecular Neurobiology. 58(7):3238-3251 (IF:5.59, ranking: 61\/273).<\/li>\n<li style=\"text-align: left\">Yen P SY\u2020, Liu YC\u2020, Chu CH, <strong><u>Chen SL*<\/u><\/strong>. Upregulation of glutamatergic receptors in hippocampus and locomotor hyperactivity in aged spontaneous hypertensive rat. <strong>2021, <\/strong>Cellular and Molecular Neurobiology, doi: 10.1007\/s10571-021-01094-3 (IF:5.05, ranking:82\/273).<\/li>\n<li>Lin YS\u2020, Liu CK\u2020, Lee HC, Chou MC, Ke LY, Chen CH, &amp; <strong><u>Chen SL<\/u><\/strong><sup>*<\/sup>. Electronegative very-low-density lipoprotein induces brain inflammation and cognitive dysfunction in mice. <strong>2021<\/strong>, Scientific Reports, 11(1):6013. (IF: 4.379, ranking: 17\/73)<\/li>\n<li style=\"text-align: left\">Lu RB, Chang YH, Wang TY, Lee SY, Chen PS, Yang YK, Hong JS, <strong><u>Chen SL<\/u><\/strong>*. Dextromethorphan attenuated chronic valproic acid-induced neutrophils downregulation in Han Chinese patients with bipolar disorder. Clinical Psychopharmacology and Neuroscience, <strong>2020<\/strong>. Feb; 18(1): 145-152.\u00a0 (IF: 2.567).<\/li>\n<li style=\"text-align: left\">LI DJ, <strong><u>Chen SL<\/u><\/strong>,\u00a0Chang YP, Yen CF*. Factors Affecting Painkillers, Sedatives\/Hypnotics, Nicotine, and Unhealthy Alcohol Use Among Gay and Bisexual Men in Taiwan. Int J Environ Res Public Health.\u00a0<strong>2020<\/strong> Jan 29;17(3) (IF: 2.9, ranking: 105\/265)<\/li>\n<li>Li CL, Lee HC, Chu CH, Chou MC, Liu CK, Chen CH, Lin YS, <strong><u>Chen SL<\/u><\/strong>*. Immunoregulatory effects of very low density lipoprotein from healthy and metabolic syndrome individuals on glia. Immunobiology,<strong> 2019<\/strong><strong>,<\/strong> 224: 632 (IF: 2.873).<\/li>\n<li>Lu RB, Lee SY, Wang TY, Chang YH, Chen PS, Chu CH, Yang YK, Hong JS, <strong><u>Chen SL*<\/u><\/strong>.\u00a0Long-term heroin use was associated with the downregulation of systemic platelets, BDNF, and TGF-\u03b21, and it contributed to the disruption of executive function in Taiwanese Han Chinese. <strong>2017<\/strong>. Drug and Alcohol Dependence 179:139-145. (IF: 3.222, ranking: 4\/18)<\/li>\n<li>Lee SY, <strong><u>Chen SL<\/u><\/strong>, Wang TY, Chang YH, &#8230;..Lu RB*. The COMT Val158Met Polymorphism\u00a0Is Associated With Response to Add-on Dextromethorphan Treatment in Bipolar Disorder. J. Clin Psychopharmacol. <strong>2017<\/strong>; 37(1):94-98. (IF: 2.891)<\/li>\n<li>Lee SY, Wang TY, <strong><u>Chen SL<\/u><\/strong>, Chang YH, &#8230;&#8230;Lu RB, Chen CS*. The correlation between plasma BDNF and cognitive function in bipolar disorder is modulated by the BDNF Val66Met polymorphism. Scientific Reports, <strong>2016<\/strong>, 6:37950. (IF: 5.228).<\/li>\n<li>Wang TY, Lee SY, <strong><u>Chen SL<\/u><\/strong>, Chang YH, &#8230;..Hong JS, Lu RB*.\u00a0 Comparing clinical responses and the biomarkers of BDNF and cytokines between subthreshold bipolar disorder and bipolar II disorder. Scientific Reports. <strong>2016<\/strong>; 6:27431. (IF: 5.228)<\/li>\n<li>Chang TT, <strong><u>Chen SL<\/u><\/strong>, Chang YH, Chen PS, &#8230;.Hong JS, Lu RB, Lee SY*. The DRD3 Ser9Gly Polymorphism Predicted Metabolic Change in Drug-Naive Patients With Bipolar II Disorder. Medicine.\u00a0<strong>2016<\/strong>; 95(24):e3488. (IF: 1.803)<\/li>\n<li>Lee SY#, <u><strong>Chen<\/strong><\/u><u><strong> SL#<\/strong><\/u><strong><u>,<\/u><\/strong> Chang YH, Chen PS, &#8230;..Hong JS &amp; Lu RB*<strong>.<\/strong> Low-dose memantine attenuated methadone dose in opioid dependent patients: a 12-week double-blind randomized controlled trial. Scientific Reports<strong>. 2015<\/strong>, 19;5:10140. (IF: 5.228)<\/li>\n<li>Lee SY, <strong><u>Chen<\/u><\/strong><strong><u> SL<\/u><\/strong>, Chang YH, Chu CH, &#8230;&#8230;.Hong JS, Lu RB*. A Placebo-Controlled Trial of Dextromethorphan as an Adjunct in Opioid-Dependent Patients Undergoing Methadone Maintenance Treatment. International Journal of Neuropsychopharmacology. <strong>2015<\/strong>; 18(7). (IF: 4.333)<\/li>\n<li>Chang YH, <strong><u>Chen<\/u><\/strong><strong><u> SL<\/u><\/strong>, Lee SY, Chen PS, Wang TY, Lee HI, Chen KC, Yang YK, Hong JS &amp; Lu RB*. Low-dose add-on memantine treatment may improve cognitive performance and self-reported health conditions in opioid-dependent patients undergoing methadone-maintenance-therapy<strong>.<\/strong> Scientific Reports. <strong>2015<\/strong>; 5:9708. (IF: 5.228)<\/li>\n<li>Lee SY,<strong><u> Chen SL<\/u><\/strong>, Chang YH, Chen PS, &#8230;&#8230;Hong JS, Lu RB. ALDH2 polymorphism associated with attenuating negative symptoms in patients with schizophrenia treated with add-on dextromethorphan.\u00a0J Psychiatr Res. <strong>2015<\/strong>; 69:50-6. (IF: 4.465).<\/li>\n<li><strong><u>Chen SL<\/u><\/strong>, Lee SY, Chang YH, Chen PS, Lee IH, Wang TY, Chen KC, Yang YK, Hong JS, Lu RB*. Therapeutic effects of add-on low-dose dextromethorphan plus valproic acid in bipolar disorder. <strong>2014<\/strong>, European Neuropsychopharmacology. 24(11):1753-9 (IF: 5.4, R\/C: 35\/253).<\/li>\n<li>Lee SY,\u00a0<strong><u>Chen SL,<\/u><\/strong>\u00a0Chang YH, Chen PS, Huang SY&#8230;..Hong JS, Lu RB*.\u00a0The effects of add-on low-dose memantine on cytokine levels in bipolar II depression: a 12-week double-blind, randomized controlled trial. J Clin Psychopharmacol.\u00a0<strong>2014<\/strong>; 34 (3):337-43. (IF: 3.8, R\/C: 47\/254).<\/li>\n<li><strong><u>Chen SL*<\/u><\/strong>, Lee SY, Chang YH, Chu CH, Chen SH, Wang TY, Chen PS, Lee IH, Yang YK, Hong JS, Lu RB<sup>*<\/sup>. The <em>BDNF<\/em> Val66Met polymorphism and plasma BDNF level in Han Chinese patients with bipolar disorder, and schizophrenia. Progress in Neuro-Psyhcopharmacology and Biological Psychiatry<em>. <\/em><strong>2014<\/strong>; 51:99-104 (IF: 4.1, R\/C: 36\/254).<\/li>\n<li><strong><u>Chen SL<\/u><\/strong>, Lee SY, Tao PL, &#8230;..Hong JS, Lu RB*. Dextromethorphan Attenuated Inflammation and Combined Opioid Use in Humans Undergoing Methadone Maintenance Treatment. <em>Journal of Neuroimmune Pharmacology<\/em>. <strong>2012<\/strong>. 7:1025\u20131033\u00a0 (IF:4.58, R\/C: 30\/261).<\/li>\n<li><strong><u>Chen SL<\/u><\/strong>, Lee SY, Chang YH, &#8230;.Yang YK, Lu RB*. Inflammation in patients with schizophrenic: the therapeutic benefits of risperidone plus add-on dextromethorphan.<em> Journal of Neuroimmune Pharmacology.<\/em> <strong>2012<\/strong>. 7(3):656\u2013664. (IF:4.58)<\/li>\n<li><strong><u>Chen SL<\/u><\/strong>, Tao PL, Chu CH, Chen SH, Hong JS, Lu RB*. Low-dose memantine attenuated morphine addictive behavior through its anti-inflammation and neurotrophic effects in rats. <em>Journal of Neuroimmune Pharmacology.<\/em> <strong>2012<\/strong>. 7(2):444-53. (IF:4.58)<\/li>\n<li><strong><u>Chen<\/u><\/strong><strong><u> SL<\/u><\/strong>, Hsu KY, Huang EYK, Lu RB, Tao PL*. Low doses of dextromethorphan attenuate morphine-induced rewarding via the sigma-1 receptor at ventral tegmental area in rats. <em>Drug and Alcohol Dependence<\/em>. <strong>2011<\/strong>. 117 (2-3):164-9. (SCI, IF: 3.38, Ranking: 3\/14, Substance Abuse)<\/li>\n<li><strong><u>Chen SL<\/u><\/strong>, Ma H.I., Han J.M., Lu RB, Tao PL<strong>*<\/strong>, Law P.Y., Loh H.H. Antinociceptive effects of morphine and naloxone in mu-opioid receptor knockout mice transfected with the MORS196A gene. <em>Journal of biomedical science<\/em>, <strong>2010<\/strong> Apr, 17:28. (SCI, IF: 1.98, Ranking: 63\/112).<\/li>\n<li><strong><u>Chen SL<\/u><\/strong>, MA HI, HAN JM, TAO PL, LAW PY, LOH H.H. DsAAV type 2-mediated gene transfer of MORS196A-EGFP into spinal cord as a pain management paradigm.<em> Proc Natl Acad Sci U S A. <\/em><strong>2007 <\/strong>Dec, 104 (50), 20096-101. (SCI; IF: 9.68, Ranking: 3\/55).<\/li>\n<li><strong><u>Chen SL<\/u><\/strong>, Huang EY, Chow LH, Tao PL*. Dextromethorphan differentially affects opioid antinociception in rats. <em> J. Pharmacol<\/em>., <strong>2005<\/strong>, 144(3), 400-404. (SCI; IF: 4.41, Ranking: 35\/261)<\/li>\n<\/ol>\n<p><strong><u>International conference (within 5 years)<\/u><\/strong><strong><u>:<\/u><\/strong><\/p>\n<ol>\n<li>Fan Y, Chou MC, Yu YA, Chu CH, Liu YC, Liu CK, Chen CH,<strong> Chen SL*<\/strong>. Intermittent hypoxia increases brain glutamatergic receptors and anxiety behavior in a mouse model of sleep apnea. 14th Asia Pacific Federation of Pharmacologists (APFP 2021, Taipei, Taiwan).<\/li>\n<li>Yen P SY, Liu YC, Hsieh YH, Chen SC, Chu CH, <strong>Chen SL*<\/strong>. Locomotor hyperactivity and up-regulation of hippocampal glutamatergic receptors in aged spontaneous hypertensive rat. 14th Asia Pacific Federation of Pharmacologists (APFP 2021, Taipei, Taiwan).<\/li>\n<li>Lu RB, Chang YH, Lee SY, <strong>Chen SL*<\/strong>. Dextromethorphan protect the valproic acid induced down regulation of neutrophils in patients with bipolar disorder. <strong>2020<\/strong> Japan Neuroscience meeting (online oral presentation, Japan).<\/li>\n<li>Lin YS, Lee HC, Chou MC, Liu CK, Chen CH, Ke LY, Fan Y<sub>, <\/sub><strong>Chen SL*<\/strong>. Very-low-density lipoprotein from metabolic syndrome patient-facilitated heart dysfunction, brain microglia expression and cognitive dysfunction in mice- from heart to brain. <strong>2019<\/strong> Japan Neuroscience meeting (Toki Messe, Japan).<\/li>\n<li><u><strong>Chen SL<\/strong><\/u><u><strong>,<\/strong><\/u>\u00a0Lin YS,\u00a0Chou MC,\u00a0Lee HC, Chen CH,\u00a0Liu CK. Very low density lipoprotein from metabolic syndrome patients induces glia cell activation and cognitive impairment in mice. <strong>2018<\/strong> Federation of Europe Neuroscience Societies\u00a0(FENS) meeting (Berlin, Germany)<\/li>\n<li>Chou MC, <strong><u>Chen SL,<\/u><\/strong> Chen CJ, Ke LY, Tsai MH, Lai CL, Chen CH, Liu CK*. Electronegative Low-Density Lipoprotein is Associated with Clinical Progression of Alzheimer\u2019s Disease. Presented at <em>Cell Symposia: Aging and Metabolism <\/em>in Sitges, <strong>2018<\/strong>, Spain. September 23-25.<\/li>\n<li>Li CL, Lin YS, Lee HC, Chen CH, <strong><u>Chen <\/u><\/strong><strong><u>SL*<\/u><\/strong>. <strong>2017<\/strong>. Negative charged very low density lipoprotein induced neuronal inflammation and cognitive dysfunction <em>in vitro<\/em> and <em>in vivo<\/em>. University of Cologne-Kaohsiung Medical University Joint Symposium (Kaohsiung, Taiwan)<\/li>\n<li><strong><u>Chen SL<\/u><\/strong><strong><u>,<\/u><\/strong> Lee SY, Wang TY, Li CL, Lu RB*. <strong>2017<\/strong>. Plasma BDNF levels correlated to the executive function and platelet counts but not <em>BDNF<\/em> Val66Met polymorphism in Han Chinese with long term heroin used. Asia Pacific Society for alcohol and addiction research. (Taipei, Taiwan) (invited speaker)<\/li>\n<li><u><strong>Chen<\/strong><\/u><u><strong> SL*<\/strong><\/u><strong>,<\/strong> Lee HC, Chou MC, Ke LY, Lai CL, Chen CH*, Liu CK*, <strong>2016<\/strong>.\u00a0Very low density-lipoprotein induced neuronal inflammation and cognitive dysfunction in mice. Neuroscience meeting (San Diego, USA)<\/li>\n<li><b><strong><u>Chen<\/u><\/strong><strong><u> SL*<\/u><\/strong><strong>,<\/strong> <\/b>Lu RB*, <strong>2015<\/strong>. Long term opioid use induces systemic inflammation and down regulation of TGF-\u03b21 and BDNF. Neuroscience meeting (Chicago, USA)<\/li>\n<\/ol>\n<p><u><strong>Domestic conference (within 5 years)<u><strong>:<\/strong><\/u><\/strong><\/u><\/p>\n<ol>\n<li><strong><u>Chen SL<\/u><\/strong>,\u00a0Ma HI,\u00a0Han JM,\u00a0Tao PL,\u00a0Law PY\u00a0and\u00a0Loh HH. <strong>(2016)<\/strong> DsAAV mediated gene transfer of mutant \u03bc-opioid receptors as a pain management paradigm. The 31<sup><span style=\"font-size: small\">th<\/span><\/sup> Joint Annual Conference of Biomedical sciences, Taipei, Taiwan R.O.C. (invited speaker)<\/li>\n<li>Lin YS, Chou MC, Lee HC, Chen CH, Chen SL<sup>*<\/sup>. Very low density lipoprotein from metabolic syndrome subject induced neuronal inflammation and cognitive dysfunction in mice. <strong>2018 <\/strong>\u751f\u7269\u91ab\u5b78\u806f\u5408\u6703\u8b70 The 34<sup>th<\/sup> Joint Annual Conference of Biomedical sciences, (\u53f0\u5317,\u53f0\u7063).<\/li>\n<\/ol>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u9673 \u79c0 \u862d\u00a0 \u00a0\u6559 \u6388 (Professsor, Shiou-Lan Chen) &hellip; <a href=\"https:\/\/wp.kmu.edu.tw\/shioulan\/\">\u95b1\u8b80\u5168\u6587 <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":256,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"open","ping_status":"open","template":"","meta":{"_exactmetrics_skip_tracking":false,"_exactmetrics_sitenote_active":false,"_exactmetrics_sitenote_note":"","_exactmetrics_sitenote_category":0,"footnotes":""},"class_list":["post-17","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/wp.kmu.edu.tw\/shioulan\/wp-json\/wp\/v2\/pages\/17","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/wp.kmu.edu.tw\/shioulan\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/wp.kmu.edu.tw\/shioulan\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/wp.kmu.edu.tw\/shioulan\/wp-json\/wp\/v2\/users\/256"}],"replies":[{"embeddable":true,"href":"https:\/\/wp.kmu.edu.tw\/shioulan\/wp-json\/wp\/v2\/comments?post=17"}],"version-history":[{"count":147,"href":"https:\/\/wp.kmu.edu.tw\/shioulan\/wp-json\/wp\/v2\/pages\/17\/revisions"}],"predecessor-version":[{"id":214,"href":"https:\/\/wp.kmu.edu.tw\/shioulan\/wp-json\/wp\/v2\/pages\/17\/revisions\/214"}],"wp:attachment":[{"href":"https:\/\/wp.kmu.edu.tw\/shioulan\/wp-json\/wp\/v2\/media?parent=17"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}