{"id":25,"date":"2021-03-09T15:40:16","date_gmt":"2021-03-09T07:40:16","guid":{"rendered":"http:\/\/wp.kmu.edu.tw\/shuchiwang\/?p=25"},"modified":"2026-01-21T09:16:46","modified_gmt":"2026-01-21T01:16:46","slug":"%e6%ad%a1%e8%bf%8e%e5%8a%a0%e5%85%a5%e7%8e%8b%e8%bf%b0%e7%b6%ba%e8%80%81%e5%b8%ab%e5%af%a6%e9%a9%97%e5%ae%a4","status":"publish","type":"post","link":"https:\/\/wp.kmu.edu.tw\/shuchiwang\/2021\/03\/09\/%e6%ad%a1%e8%bf%8e%e5%8a%a0%e5%85%a5%e7%8e%8b%e8%bf%b0%e7%b6%ba%e8%80%81%e5%b8%ab%e5%af%a6%e9%a9%97%e5%ae%a4\/","title":{"rendered":"Welcome to Pre-Cancer Research Laboratory"},"content":{"rendered":"<p><strong><span style=\"font-size: 14pt\">\u53ef\u80fd\u6027\u7684\u751f\u7269\u56e0\u5b50\u53c3\u8207\u5728\u6162\u6027\u809d\u708e\u8a98\u767c\u809d\u764c\u4e4b\u6a5f\u5236:<\/span><br \/>\n<span style=\"font-size: 14pt\">Potential biological factors involved in the mechanism of hepatocellular carcinoma<\/span><br \/>\n<\/strong>1. \u5efa\u7acb\u8102\u80aa\u809d\u5c0f\u9f20\u6a21\u5f0f\uff0c\u5f9e\u767c\u708e\u8a98\u5c0e\u809d\u7e96\u7dad\u5316\u751a\u6216\u662f\u809d\u764c\u5176\u53ef\u80fd\u53c3\u8207\u4e4b\u764c\u524d\u75c5\u8b8a\u6a5f\u5236\u4e4b<br \/>\n\u63a2\u8a0e\u3002The MASLD mouse models to explore the possible precancerous lesion<br \/>\nmechanism of liver fibrosis or even hepatocellular carcinoma.<\/p>\n<p>2. \u958b\u767c\u6db2\u614b\u751f\u7269\u6aa2\u9ad4-Exosomes\u6aa2\u6e2c\u56e0\u5b50\uff0c\u4ee5\u6b64\u76e3\u63a7\u548c\u9810\u6e2c\u75be\u75c5\u958b\u767c\u6db2\u614b\u6aa2\u6e2c\u4e4b\u7cbe\u6e96\u91ab<br \/>\n\u7642\u7b56\u7565\u3002Utilization of liquid biological specimens for disease monitoring, prediction,<br \/>\nand the development of precision medicine strategies.<\/p>\n<p>3. HCV \u7d30\u80de\u5167\u4e0d\u540c\u75c5\u6bd2\u91cf\u5176\u548c\u764c\u75c7\u76f8\u95dc\u57fa\u56e0\u8868\u73fe\u4e4b\u63a2\u8a0e\u3002<br \/>\nDifferent viral loads in HCV cells and the expression of cancer-related genes.<br \/>\n<img loading=\"lazy\" decoding=\"async\" class=\"alignleft size-full wp-image-60\" src=\"https:\/\/wp.kmu.edu.tw\/shuchiwang\/files\/2021\/03\/research.png\" alt=\"research\" width=\"1718\" height=\"1016\" srcset=\"https:\/\/wp.kmu.edu.tw\/shuchiwang\/files\/2021\/03\/research.png 1718w, https:\/\/wp.kmu.edu.tw\/shuchiwang\/files\/2021\/03\/research-300x177.png 300w, https:\/\/wp.kmu.edu.tw\/shuchiwang\/files\/2021\/03\/research-1024x606.png 1024w, https:\/\/wp.kmu.edu.tw\/shuchiwang\/files\/2021\/03\/research-500x296.png 500w\" sizes=\"auto, (max-width: 1718px) 100vw, 1718px\" \/><\/p>\n<p><strong><span style=\"font-size: 14pt\">\u5927\u6578\u64da\u5206\u6790\u5230\u4f5c\u7528\u6a5f\u5236\u4e4b\u63a2\u8a0e:<\/span><br \/>\n<span style=\"font-size: 14pt\">Big Data Analysis and Mechanism of Action:<\/span><br \/>\n<\/strong>1.\u00a0 \u80a5\u80d6\u76f8\u95dc\u4ee3\u8b1d\u6027\u8102\u80aa\u6f14\u8b8a\u809d\u764c\u6703\u6709\u8f03\u5dee\u7684\u9810\u5f8c\u4ee5\u53ca\u7a81\u8b8a\u57fa\u56e0\u7684\u8868\u73fe\u3002<br \/>\nObesity-related MASLD-derived hepatocellular carcinoma is associated with poorer<br \/>\nprognosis and susceptibility gene variants.<\/p>\n<p>2.\u00a0 \u57fa\u56e0\u548c\u5fae\u5c0fRNA\u8868\u73fe\u5728\u9577\u671f\u4f4e\u6fc3\u5ea6\u6f5b\u4f0fC\u578b\u809d\u708e\u75c5\u6bd2\u611f\u67d3\u548c\u764c\u767c\u53ca\u9810\u5f8c\u4e4b\u76f8\u95dc\u6a5f\u5236\u3002<br \/>\nmRNA and miRNA networks in long-term low hepatitis C virus loads and cancer<br \/>\ndevelopment and prognosis.<\/p>\n<p>3. \u591a\u9ad4\u5b78\u7814\u7a76\u5de8\u566c\u7d30\u80de\u5728\u816b\u7624\u8f49\u79fb\u4e2d\u86cb\u767d\u8abf\u63a7\u4e4b\u76f8\u95dc\u63a2\u8a0e\u3002<br \/>\nMulti-omics studies exploring protein regulation of macrophages in tumor metastasis.<br \/>\n<strong><br \/>\n<\/strong>4.\u00a0 Corylin\u8abf\u63a7\u6d3b\u5316\u8166\u5167\u5de8\u566c\u7d30\u80de-Microgila\u4e4bNLRP3 inflammasome\u3002<br \/>\nCorylin regulates NLRP3 inflammasome activation in brain microglia.<\/p>\n<p>5.\u00a0 \u4fee\u5fa9\u86cb\u767d\u78f7\u9178\u5316\u548c\u7d30\u80de\u9031\u671f\u53ca\u5176DNA\u96d9\u80a1\u65b7\u88c2\u4fee\u5fa9\u4e4b\u8abf\u63a7\u6a5f\u5236\u3002<br \/>\nRepair protein phosphorylation, cell cycle, and DNA double-strand break repair.<br \/>\n<strong><a href=\"https:\/\/wp.kmu.edu.tw\/shuchiwang\/files\/2021\/03\/\u5716\u72472.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignleft size-full wp-image-58\" src=\"https:\/\/wp.kmu.edu.tw\/shuchiwang\/files\/2021\/03\/\u5716\u72472.jpg\" alt=\"\u5716\u72472\" width=\"1740\" height=\"859\" srcset=\"https:\/\/wp.kmu.edu.tw\/shuchiwang\/files\/2021\/03\/\u5716\u72472.jpg 1740w, https:\/\/wp.kmu.edu.tw\/shuchiwang\/files\/2021\/03\/\u5716\u72472-300x148.jpg 300w, https:\/\/wp.kmu.edu.tw\/shuchiwang\/files\/2021\/03\/\u5716\u72472-1024x506.jpg 1024w, https:\/\/wp.kmu.edu.tw\/shuchiwang\/files\/2021\/03\/\u5716\u72472-500x247.jpg 500w\" sizes=\"auto, (max-width: 1740px) 100vw, 1740px\" \/><\/a><\/strong><\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p><strong>\u00a0<\/strong><\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u53ef\u80fd\u6027\u7684\u751f\u7269\u56e0\u5b50\u53c3\u8207\u5728\u6162\u6027\u809d\u708e\u8a98\u767c\u809d\u764c\u4e4b\u6a5f\u5236: Potential biolog &hellip; <a href=\"https:\/\/wp.kmu.edu.tw\/shuchiwang\/2021\/03\/09\/%e6%ad%a1%e8%bf%8e%e5%8a%a0%e5%85%a5%e7%8e%8b%e8%bf%b0%e7%b6%ba%e8%80%81%e5%b8%ab%e5%af%a6%e9%a9%97%e5%ae%a4\/\">\u95b1\u8b80\u5168\u6587 <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":331,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"image","meta":{"_exactmetrics_skip_tracking":false,"_exactmetrics_sitenote_active":false,"_exactmetrics_sitenote_note":"","_exactmetrics_sitenote_category":0,"footnotes":""},"categories":[1],"tags":[],"class_list":["post-25","post","type-post","status-publish","format-image","hentry","category-uncategorized","post_format-post-format-image"],"_links":{"self":[{"href":"https:\/\/wp.kmu.edu.tw\/shuchiwang\/wp-json\/wp\/v2\/posts\/25","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/wp.kmu.edu.tw\/shuchiwang\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/wp.kmu.edu.tw\/shuchiwang\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/wp.kmu.edu.tw\/shuchiwang\/wp-json\/wp\/v2\/users\/331"}],"replies":[{"embeddable":true,"href":"https:\/\/wp.kmu.edu.tw\/shuchiwang\/wp-json\/wp\/v2\/comments?post=25"}],"version-history":[{"count":17,"href":"https:\/\/wp.kmu.edu.tw\/shuchiwang\/wp-json\/wp\/v2\/posts\/25\/revisions"}],"predecessor-version":[{"id":287,"href":"https:\/\/wp.kmu.edu.tw\/shuchiwang\/wp-json\/wp\/v2\/posts\/25\/revisions\/287"}],"wp:attachment":[{"href":"https:\/\/wp.kmu.edu.tw\/shuchiwang\/wp-json\/wp\/v2\/media?parent=25"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/wp.kmu.edu.tw\/shuchiwang\/wp-json\/wp\/v2\/categories?post=25"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/wp.kmu.edu.tw\/shuchiwang\/wp-json\/wp\/v2\/tags?post=25"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}