{"id":7,"date":"2013-03-19T09:06:14","date_gmt":"2013-03-19T01:06:14","guid":{"rendered":"http:\/\/wp.kmu.edu.tw\/tzengch\/?page_id=7"},"modified":"2016-01-25T11:13:44","modified_gmt":"2016-01-25T03:13:44","slug":"%e7%a0%94%e7%a9%b6%e8%91%97%e4%bd%9c","status":"publish","type":"page","link":"https:\/\/wp.kmu.edu.tw\/tzengch\/%e7%a0%94%e7%a9%b6%e8%91%97%e4%bd%9c\/","title":{"rendered":"\u7814\u7a76\u8457\u4f5c"},"content":{"rendered":"
    \n
  1. Chang, KM; Chen, HH; Wang, TC; Chen, IL; Chen, YT; Yang, SC; Chen, YL; Chang, HH; Huang, CH; Chang, JY; Shih, C; Kuo, CC*; Tzeng, CC* (2015) Novel oxime-bearing coumarin derivatives act as potent Nrf2\/ARE activators in vitro and in mouse model. Eur. J. Med. Chem<\/em>. 106, 60-74.<\/li>\n
  2. Chen, YR; Tseng, CH; Chen, YL; Hwang, TL; Tzeng, CC* (2015) Discovery of benzo[f]indole-4,9-dione derivatives as new type of anti-inflammatory agents. Int. J. Mol. Sci.<\/em> 16, 6532-6544.<\/li>\n
  3. Lo, WF; Chou, YW; Tseng, CH; Shiu, YH; Chen,YW; Yang, SC; Yeh-Long Chen, YL; Lin, MF*; Tzeng, CC* (2015) Discovery of novel N-alkyl 4-anilinofuro[2,3-b]quinoline derivatives (CIL-102 derivatives) against castration-resistant human prostate cancers Anti-Cancer Agents in<\/em> Med. Chem<\/em>. 15, 493-500.<\/li>\n
  4. Chang, KM; Liang, FP; Chen, IL; Yang, SC; Juang, SH; Wang, TC; Chen, YL; Tzeng, CC* (2015). Discovery of oxime-bearing naphthalene derivatives as a novel structural type of Nrf2 activators. Bioorg. Med. Chem<\/em>. 23, 3852-3859.<\/li>\n
  5. Tseng CH, Tzeng CC, Chiu CC, Hsu CY, Chou CK, Chen YL* (2015)\u201cDiscovery of 2-[2-(5-nitrofuran-2-yl)vinyl]quinoline derivatives as a novel type of antimetastatic agents\u201d Bioorg. Med. Chem<\/em>. 22, 141-148. (SCI, IF2013 = 2.978, 15\/54)<\/li>\n
  6. Tseng, CH; Tzeng, CC; Hsu, CY; Cheng, CM; Yang, CN*; Chen, YL*. (2015) Discovery of 3-phenylquinolinylchalcone derivatives as potent and selective anticancer agents against breast cancers. Eur. J. Med. Chem<\/em>. 97, 306-319.<\/li>\n
  7. Chen, CL; Chen, IL; Chen, JJ; Wei, DC; Hsieh, HJ; Chang, KM; Tzeng, CC; Wang, TC. (2015) Studies on the alkylation of quinolin-2(1H)-one derivatives. J. Chil. Chem. Soc<\/em>., 60, 2812-2816.<\/li>\n
  8. Lin, RW; Yang, CN; Ku, SY; Ho,CJ; Huang, SB; Yang, MC; Chang, HW; Lin, CM; Hwang, JL; Chen, YL; Tzeng, CC*; Wang, CH* (2014). CFS-1686 causes cell cycle arrest at intra-S phase by interference of interaction of topoisomerase 1 with DNA. PLoS One 9(12), e113832\/1-e113832\/14.<\/li>\n
  9. Peng, HK; Lin, IL; Lee, CC; Wang, LY; Tzeng, CC; Chang, JG; Yang, SC (2014). Synthesis and antitumor activity evaluation of anilinoquinoline derivatives by the effect on the expression of polo-like kinase. Med. Chem<\/em>. Res. 23, 1437-1446. (SCI, IF = 1.612).<\/li>\n
  10. Chen, LC; Juang, SH; Chang, KM; Tzeng, CC; Chen, JJ; Chen, IL; Wang, TC (2014). Synthesis and Antiproliferative Evaluation of Amide-Containing Anthraquinone, Xanthone, and Carbazole. Chem. Pharm<\/em>. Bull. 62, 106\u2013111.<\/li>\n
  11. Tseng, CH; Tzeng, CC; Chiu, CC; Yang, CL; Lu, PJ; Chou, CK; Liu, CY; Chen, YL (2014). Synthesis and antiproliferative evaluation of 9-methoxy-6-(piperazin-1-yl)-11H-indeno[1,2-c]quinoline-11-one derivatives. Part 4. MedChemComm. 5, 937-948.<\/li>\n
  12. Liu, YP; Chen, HL; Tzeng, CC; Lu, PJ; Lo, CW; Lee, YC; Tseng, CH; Chen, YL; Yang, CN (2013). TCH-1030 targeting on topoisomerase I induces S-phase arrest, DNA fragmentation, and cell death of breast cancer cells. Breast Cancer Res<\/em>. Treat 138(2), 383-393. (IF = 4.431)<\/li>\n
  13. Tseng, CH; Tzeng, CC; Yang, CL; Lu, PJ; Liu, YP; Chen, HL; Chen, CY; Yang, CN; Chen, YL (2013). Discovery of indeno[1,2-c]quinoline derivatives as dual topoisomerases I\/II inhibitors: Part 3. Mol. Divers. 17, 781-799. (SCI, IF = 2.861, 13\/71, CHEMISTRY, APPLIED)<\/li>\n
  14. Peng, HK; Chen, WC; Lin, YT; Tseng, CK; Yang, SY; Tzeng, CC; Lee, JC; Yang, SC (2013). Anti-hepatitis C virus RdRp activity and replication of novel anilinobenzothiazole derivatives. Antiviral Res.<\/em> 100, 269-275.<\/li>\n
  15. Tseng, CH; Chen, YL; Hsu, CY; Chen, TC; Cheng, CM; Tso, HC; Lu, YJ; Tzeng CC* (2013). Synthesis and antiproliferative evaluation of 3-phenylquinolinylchalcone derivatives against non-small cell lung cancers and breast cancers. Eur. J. Med. Chem<\/em>. 59, 274-282. (IF = 3.499, 13\/59, Chemistry, Medicinal)<\/li>\n
  16. Tseng, CH; Cheng, CM; Tzeng, CC; Peng, SI.; Yang, CL; Chen, YL (2013) Synthesis and anti-inflammatory evaluations of \u03b2-lapachone derivatives. Bioorg. Med. Chem<\/em>. 21(2), 523-531. (IF = 2.921, 17\/56, Chemistry, Organic)<\/li>\n
  17. Peng, HK; Chen, WC; Lee, JC; Yang, SY; Tzeng, CC; Lin, YT; Yang, SC (2013) Novel anilinocoumarin derivatives as agents against hepatitis C virus by the induction of IFN-mediated antiviral responses. Org. Biomol. Chem<\/em>. 11(11), 1858-1866. (IF = 3.451, 12\/56, CHEMISTRY, ORGANIC)<\/li>\n
  18. Chen YL, Tseng CH, Lu YC, Lin RW, Chen CF, Wang GJ, Ho ML, Tzeng CC* (2013) \u201cSynthesis of Aminoalkoxy Substituted 4,5-Diphenylisoxazole Derivatives as Potential Anti-osteoporotic Agents\u201d Med. Chem.<\/em> 9, 748-755. (SCI, IF = 1.373, 48\/59, CHEMISTRY, MEDICINAL)<\/li>\n
  19. Tseng CH; Li CY; Chiu CC; Hu HT; Chen YL; Tzeng CC* (2012). Combretastatin A-4 Derivatives: Synthesis and Evaluation of 2,4,5-Triary-1H-Imidazoles as Potential Agents Against H1299 (Non-Small Cell Lung Cancer). Mol. Divers.<\/em> 16(4), 697-709. (IF = 3.153, 9\/71)<\/li>\n
  20. Tseng CH; Chen YL; Yang CL; Cheng CM; Han CH; Tzeng CC*(2012). Synthesis of 6-Substituted 9-Methoxy-11H-indeno[1,2-c]quinoline-11-one Derivatives as Potential Anticancer Agents. Bioorg. Med. Chem.<\/em> 20, 4397-4404. (IF = 2.903, 16\/59)<\/li>\n
  21. Tsai, YR; Huang, LJ; Lee, MR; Chen, YL; Kuo, SC; Tzeng, CC; Hsu, MF; Wang, JP (2012). The Signaling Mechanisms Mediating the Inhibitory Effect of TCH-1116 on Formyl Peptide-Stimulated Superoxide Anion Generation in Neutrophils Eur. J. Pharmacol<\/em>. 682, 171-180. (IF = 2.516, 108\/261)<\/li>\n
  22. Fang, YP; Wu, PC; Tzeng, CC; Chen, YL; Lin, HL; Tsai, YH (2012). A New Antitumor Agent, (3-Chloro-7-methoxyfuro[2,3-b]-quinolin-4-yl)- (4-methoxyphenyl)amine Loaded in Solid Liquid Nanoparticles: Characterization and Pharmacokinetics. Curr. Nanosci<\/em>. 8, 266-273. (IF = 1.776, 76\/231)<\/li>\n
  23. Fang, YP; Wu, PC; Huang, YB; Tzeng, CC; Chen, YL; Hung, YH; Tsai, MJ; Tsai, YH. (2012) Modification of polyethylene glycol onto solid lipid nanoparticles encapsulating a novel chemotherapeutic agent (PK-L4) to enhance solubility for injection delivery Inter. J. Nanomedicine<\/em> 7, 4995-5005. (IF = 3.13)<\/li>\n
  24. Tseng, CH; Tzeng, CC; Shih, PK; Yang, CN; Chuang, YC; Peng, SI.; Lin, CS; Wang, JP; Cheng, CM; Chen, YL (2012). Identification of Furo[3′,2′:3,4]naphtho[1,2-d]imidazole Derivatives as Orally Active and Selective Microsomal Prostaglandin E2 Synthase-1 Inhibitors (mPGES-1). Mol. Divers.<\/em> 16, 215-229. (IF = 3.153, 9\/71)<\/li>\n
  25. Peng, HK; Lin, CK; Yang, SY; Tseng, CK; Tzeng, CC; Lee, JC; Yang, SC (2012). Synthesis and Anti-HCV Activity Evaluation of Anilinoquinoline Derivatives Bioorg. Med. Chem<\/em>. Lett. 22, 1107-1110. (IF = 2.554, 21\/56)<\/li>\n
  26. Tseng CH; Tzeng CC*; Chung KY; Kao CL; Hsu CY; Cheng CM; Huang KS; Chen YL (2011). Synthesis and antiproliferative evaluation of 6-aryl- 11-iminoindeno[1,2-c]quinoline derivatives. Bioorg. Med. Chem.<\/em> 19, 7653-7663.<\/li>\n
  27. Chen, YW; Chen, YL; Tseng, CH; Liang, CC; Yang, CN; Yao, YC; Lu, PJ; Tzeng CC* (2011). \u201cDiscovery of 4-Anilinofuro[2,3-b]quinoline Derivatives as Selective and Orally Active Compounds Against Non-small Cell Lung Cancers\u201d J. Med. Chem.<\/em> 54, 4446-4461. (IF = 5.207, 3\/54)<\/li>\n
  28. Tseng CH, Lin RW, Chen YL, Wang GJ, Ho ML, Tzeng CC* (2011) \u201cDiscovery of Indeno[1,2-c]quinoline Derivatives as Inhibitors of Osteoclastogenesis Induced by Receptor Activator of NF-kB Ligand (RANKL)\u201d J. Med. Chem<\/em>. 54, 3103-3107. (IF = 5.207, 3\/54)<\/li>\n
  29. Tseng CH, Chen YL, Chung KY, Wang CH, Peng SI, Cheng CM, Tzeng CC* (2011) \u201cSynthesis and antiproliferative evaluation of 2,3-diarylquinoline derivatives\u201d Org. Biomol. Chem<\/em>. 9, 3205-3216. (IF = 3.451, 12\/56)<\/li>\n
  30. Chen, PY; Wang, TP; Chiang, MY.; Huang, KS; Tzeng, CC; Chen, YL; Wang, EC. (2011) \u201cEnvironmentally Benign Syntheses of Flavanones\u201d Tetrahedron<\/em> 67, 4155-4160. (IF = 3.011, 14\/56)<\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"

    Chang, KM; Chen, HH; Wang, TC; Chen, IL; Chen, YT; Yang … \u95b1\u8b80\u5168\u6587 \u7814\u7a76\u8457\u4f5c<\/span> →<\/span><\/a><\/p>\n","protected":false},"author":17,"featured_media":0,"parent":0,"menu_order":1,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_exactmetrics_skip_tracking":false,"_exactmetrics_sitenote_active":false,"_exactmetrics_sitenote_note":"","_exactmetrics_sitenote_category":0,"footnotes":""},"class_list":["post-7","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/wp.kmu.edu.tw\/tzengch\/wp-json\/wp\/v2\/pages\/7","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/wp.kmu.edu.tw\/tzengch\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/wp.kmu.edu.tw\/tzengch\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/wp.kmu.edu.tw\/tzengch\/wp-json\/wp\/v2\/users\/17"}],"replies":[{"embeddable":true,"href":"https:\/\/wp.kmu.edu.tw\/tzengch\/wp-json\/wp\/v2\/comments?post=7"}],"version-history":[{"count":10,"href":"https:\/\/wp.kmu.edu.tw\/tzengch\/wp-json\/wp\/v2\/pages\/7\/revisions"}],"predecessor-version":[{"id":41,"href":"https:\/\/wp.kmu.edu.tw\/tzengch\/wp-json\/wp\/v2\/pages\/7\/revisions\/41"}],"wp:attachment":[{"href":"https:\/\/wp.kmu.edu.tw\/tzengch\/wp-json\/wp\/v2\/media?parent=7"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}