{"id":8,"date":"2013-03-19T09:21:01","date_gmt":"2013-03-19T01:21:01","guid":{"rendered":"http:\/\/wp.kmu.edu.tw\/yeloch\/?page_id=8"},"modified":"2013-03-19T09:46:14","modified_gmt":"2013-03-19T01:46:14","slug":"%e7%a0%94%e7%a9%b6%e8%91%97%e4%bd%9c","status":"publish","type":"page","link":"https:\/\/wp.kmu.edu.tw\/yeloch\/%e7%a0%94%e7%a9%b6%e8%91%97%e4%bd%9c\/","title":{"rendered":"\u7814\u7a76\u8457\u4f5c"},"content":{"rendered":"<p align=\"center\"><b>2013<\/b><\/p>\n<ol>\n<li><b>Chen YL, <\/b>Tseng CH, Lo YC,<b> <\/b>Lin RW, Chen CF, Wang GJ, Ho ML, Tzeng CC \u201c<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23061562\">Synthesis of aminoalkoxy substituted 4,5-diphenylisoxazole derivatives as potential anti-osteoporotic agents<\/a>\u201d <i>Med, Chem.<\/i> <b>2013<\/b>, in pressed. (SCI, IF<sub>2011<\/sub> = 1.496, 42\/59 = 71.2%)<\/li>\n<li>Lin KL, Chien CM, Tseng CH, <b>Chen YL<\/b>, Chang LS, Lin SR \u201c<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/22505597\">Furano-1,2-Naphthoquinone Inhibits src and pi3k\/akt Signaling Pathways in ca9-22 Human Oral Squamous Carcinoma Cells<\/a>\u201d <i>Integr. Cancer Ther. <\/i><b>2012<\/b><i>,<\/i> in pressed. (SCI, IF<sub>2011<\/sub> = 2.136, 6\/22 = 27.3%)<\/li>\n<li>Tseng CH, Cheng CM, Tzeng CC, Peng SI, Yang CL,<b> Chen YL*<\/b> \u201c<a href=\"http:\/\/www.sciencedirect.com\/science\/article\/pii\/S0968089612008711\">Synthesis and Anti-inflammatory Evaluations of \u03b2-Lapachone Derivatives<\/a>\u201d, <i>Bioorg. Med. Chem.<\/i><b> <\/b><b>2013<\/b>, <i>21<\/i>, 523-531. (SCI, IF<sub>2011<\/sub> = 2.921; R\/C = 21\/59, CHEMISTRY, MEDICINAL)<\/li>\n<li>Hsieh CY, Tsai PC, Tseng CH, Chen YL, Chang LS, Lin SR* \u201c<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23064031\">Inhibition of EGF\/EGFR activation with naphtho[1,2-b]furan-4,5-dione blocks migration and invasion of MDA-MB-231 cells<\/a>\u201d <i>Toxicology in Vitro, <\/i><b>2013,<\/b><i> 27, <\/i>1-10.<i> <\/i><\/li>\n<li>Tseng CH, <b>Chen YL, <\/b>Hsu CY, Chen TC, Cheng CM, Tso HC, Lu YJ, Tzeng CC* \u201c<a href=\"http:\/\/www.sciencedirect.com\/science\/article\/pii\/S0223523412006964\">Synthesis and antiproliferative evaluation of 3-phenylquinolinylchalcone derivatives against non-small cell lung cancers and breast cancers<\/a>\u201d<i> Eur. J. Med. Chem.<\/i><b> <\/b><b>2013<\/b>, <i>59<\/i>, 274-282. (SCI, IF<sub>2011<\/sub> = 3.346; R\/C = 13\/59, CHEMISTRY, MEDICINAL)<\/li>\n<\/ol>\n<p align=\"center\"><b>2012<\/b><\/p>\n<ol>\n<li>Liu WH, <b>Chen YL<\/b>, Chang LS \u201cCIL-102 induces matrix metalloproteinase-2 (MMP-2)\/MMP-9 down-regulation via simultaneous suppression of genetic transcription and mRNA stability\u201d <i>Int. J. Biochem. Cell Biol. <\/i><b>2012, <\/b><i>44, <\/i>2212-2222.<i> <\/i>(SCI, IF<sub>2011<\/sub> = 4.634, 67\/289 = 23.2%)<\/li>\n<li>Tseng CH, Li CY, Chiu CC, Hu HT, Han CH, <b>Chen YL,*<\/b> Tzeng CC* \u201cCombretastatin A-4 Derivatives: Synthesis and Evaluation of 2,4,5-Triaryl-1<i>H<\/i>&#8211; imidazoles as Potential Agents Against H1299 (Non-small Cell Lung Cancer Cell)\u201d <i>Mol. Divers.<\/i> <b>2012<\/b>, <i>16<\/i>(4), 697-709. (SCI, IF<sub>2011<\/sub> = 3.153, 9\/71 = 12.7%)<\/li>\n<li>Fang YP, Wu PC, Huang YB, Tzeng CC,<b> Chen YL<\/b>, Hung YH, Tsai MJ, Tsai YH \u201cModification of polyethylene glycol onto solid lipid nanoparticles encapsulating a novel chemotherapeutic agent (PK-L4) to enhance solubility for injection delivery\u201d <i>Int. J. Nanomed.<\/i> <b>2012<\/b>, <i>7<\/i>, 4995-5005. (SCI, IF<sub>2011<\/sub> = 3.130; R\/C = 70\/261, \u00a0PHARMACOLOGY &amp; PHARMACY)<\/li>\n<li>Chang MY, Tai HY, <b>Chen YL<\/b>, Hsu RT \u201cSynthesis of 1,3-diaryl-1H-benzo[g]indazoles\u201d<i> Tetrohedron, <\/i><b>2012<\/b><i>, 68,<\/i> 7941-7948. (SCI, IF<sub>2011<\/sub> = 3.025, 16\/56 = 28.6%)<\/li>\n<li>Chang MY, Wu MH, <b>Chen YL<\/b> \u201cSynthesis of dihydrobenzoimidazo[2,1-a]isoquinolines\u201d <i>Tetrahedron Letts.<\/i> <b>2012<\/b>, <i>53<\/i>, 4156-4160. (SCI, IF<sub>2011<\/sub> = 2.683, 19\/56 = 33.9%)<\/li>\n<li>Chang MY, Huang YP, Lee TW, <b>Chen YL<\/b> \u201cSynthesis of dizocilpine\u201d <i>Tetrohedron, <\/i><b>2012<\/b><i>, 68,<\/i> 3283-3287. (SCI, IF<sub>2011<\/sub> = 3.025, 16\/56 = 28.6%)<\/li>\n<li>Tsai YR, Huang LJ, Lee MR, <b>Chen YL<\/b>, Kuo SC, Tzeng CC, Hsu MF, Wang JP \u201c<a href=\"http:\/\/www.sciencedirect.com\/science\/article\/pii\/S0014299912001525\">The signaling mechanisms mediating the inhibitory effect of TCH-1116 on formyl peptide-stimulated superoxide anion generation in neutrophils<\/a>\u201d <i>Eur. J. Pharm. <\/i><b>2012<\/b><i>, 682,<\/i> 171-180. (SCI, IF<sub>2011<\/sub> = 2.516, 108\/261 = 41.4%)<\/li>\n<li>Fang YP, Wu PC, Tzeng CC, Chen YL, Lin HL, Tsai YH \u201cA New Antitumor Agent, (3-chloro-7-methoxyfuro[2,3-b]-quinolin-4-yl)-(4-methoxyphenyl) amine, Loaded in Solid Lipid Nanoparticles: Characterization and Pharmacokinetics\u201d <i>Curr. Nanosci., <\/i><b>2012<\/b><i>, 8,<\/i> 266-273. (SCI, IF<sub>2011<\/sub> = 1.776, 76\/231 = 32.9%)<\/li>\n<li>Tseng CH, <b>Chen YL, <\/b>Yang CL,<b> <\/b>Cheng CM, Han CH, Tzeng CC \u201cSynthesis of 6-Substituted 9-Methoxy-11H-indeno[1,2-c]quinoline-11-one Derivatives as Potential Anticancer Agents\u201d <i>Bioorg. Med. Chem.<\/i> <b>2012<\/b>, <i>20<\/i>, 4397-4404. (SCI, IF<sub>2011<\/sub> = 2.921, 17\/56 = 30.4%)<\/li>\n<li>Tseng CH, Tzeng CC, Shih PK, Yang CN, Chuang YC, Peng SI, Lin CS, Wang JP, Cheng CM, <b>Chen YL<\/b>* \u201cIdentification of Furo[3&#8242;,2&#8242;:3,4]naphtho[1,2-<i>d<\/i>]imidazole Derivatives as Orally Active and Selective Inhibitors of \u00a0Microsomal Prostablandin E<sub>2<\/sub> Synthase-1 (mPGES-1)\u201d <i>Mol. Divers.<\/i> <b>2012<\/b>, <i>16<\/i>, 215-229. (SCI, IF<sub>2011<\/sub> = 3.153, 9\/71 = 12.7%)<\/li>\n<\/ol>\n<p align=\"center\"><b>2011<\/b><b><\/b><\/p>\n<ol>\n<li>Tseng CH, Tzeng CC, Chung KY, Kao CL, Hsu CY, Cheng CM, Hung KS, <b>Chen YL<\/b>* \u201cSynthesis and antiproliferative evaluation of 6-aryl-11-iminoindeno[1,2-c]quinoline derivatives\u201d <i>Bioorg. Med. Chem.<\/i> <b>2011<\/b>, <i>19<\/i>, 7653-7663. (SCI, IF<sub>2010<\/sub> = 2.978, 15\/54)<\/li>\n<li>Chang MY, Tai HY, <b>Chen YL<\/b> \u201cSynthesis of rodocaine.\u201d <i>Tetrahedron <\/i><b>2011<\/b>,<i> 67, <\/i>7673-7680. (SCI, IF<sub>2010<\/sub> = 3.011, 14\/56)<\/li>\n<li>Kao CL, Tang YH, Lin YC, Chiu LT, Chen HT, Hsu SC, Hsieh KC, Lu CY, <b>Chen YL<\/b><b> <\/b>\u201cCopper complex of a pyridine-modified poly(amidoamine) dendrimer as a chemical nuclease: synthetic and catalytic study.\u201d <i>Nanomedicine<\/i> <b>2011<\/b>, <i>7<\/i>, 273-276. (SCI, IF<sub>2010<\/sub> = 6.202, 12\/160)<\/li>\n<li>Chang MY, Lee MF, <b>Chen YL<\/b> \u201cSynthesis of tetrahydrobenzoisoquinolinols, tetrahydropyrindines, and hexahydroquinolines from 4-aryltetrahydropyridines.\u201d<i> <\/i><i>Tetrahedron <\/i><b>2011<\/b>,<i> 67, <\/i>4552-4558. (SCI, IF<sub>2010<\/sub> = 3.011, 14\/56)<\/li>\n<li>Chen YW, <b>Chen YL<\/b>, Tseng CH, Liang CC, Yang CN, Yao YC, Lu PJ, Tzeng CC \u201cSynthesis, Pharmacokinetic, and Anticancer Evaluations of Certain 4-Anilinofuro[2,3-<i>b<\/i>]quinoline Derivatives\u201d<i> J. Med. Chem.<\/i> <b>2011<\/b>, <i>54<\/i>, 4446-4461. (SCI, IF<sub>2010<\/sub> = 5.207, 3\/54)<\/li>\n<li>Chen PY, Wang TP, Chiang MY, Huang KS, Tzeng CC, <b>Chen YL,<\/b> Wang EC \u201cEnvironmentally benign syntheses of flavanones\u201d <i>Tetrahedron,<\/i> <b>2011<\/b>, <i>67<\/i>, 4155-4160. (SCI, IF<sub>2010<\/sub> = 3.011, 14\/56)<\/li>\n<li>Tseng CH, Lin RW, <b>Chen YL<\/b>, Wang GJ, Ho ML, Tzeng CC* \u201cDiscovery of Indeno[1,2-<i>c<\/i>]quinoline Derivatives as Inhibitors of Osteoclastogenesis Induced by Receptor Activator of NF-kB Ligand (RANKL)\u201d <i>J. Med. Chem.<\/i> <b>2011<\/b>, <i>54<\/i>, 3103-3107. (SCI, IF<sub>2010<\/sub> = 5.207, 3\/54)<\/li>\n<li>Tseng CH, <b>Chen YL<\/b>, Chung KY, Wang CH, Peng SI, Cheng CM, Tzeng CC* \u201cSynthesis and antiproliferative evaluation of 2,3-diarylquinoline derivatives\u201d <i>Org. Biomol. Chem.<\/i> <b>2011<\/b>, <i>9<\/i>, 3205-3216. (SCI, IF<sub>2010<\/sub> = 3.451, 12\/56)<\/li>\n<li>Lee CL, Huang CH, Wang HC, Chuang DW, Wu MJ, Wang SY, Hwang TL, Wu CC, <b>Chen YL<\/b>, Chang FR, Wu YC. \u201cFirst total synthesis of antrocamphin A and its analogs as anti-inflammatory and anti-platelet aggregation agents.\u201d<i> Org. Biomol. Chem.<\/i> <b>2011<\/b>, <i>9<\/i>, 70-73. (SCI, IF<sub>2010<\/sub> = 3.451, 12\/56)<\/li>\n<\/ol>\n<p align=\"center\"><b>2010<\/b><\/p>\n<ol>\n<li>Su JC, Lin KL, Chien CM, Tseng CH, <b>Chen YL<\/b>, Chang LS, Lin SR \u201cFurano-1,2-naphthoquinone inhibits EGFR signaling associated with G2\/M cell cycle arrest and apoptosis in A549 cells\u201d <i>Cell Biochem. Funct.<\/i> <b>2010<\/b>, <i>28<\/i>, 695\u2013705. (SCI, IF<sub>2008<\/sub> = 1.515, 213\/283)<\/li>\n<li>Chang MY, Lin CH, <b>Chen YL<\/b>, Hsu RT, Chang CY \u201cPd<sub>2<\/sub>(dba)<sub>3<\/sub>-promoted synthesis of 3-N-substituted 4-aryl-1,2,3,6-tetrahydropyridine\u201d <i>Tetrahedron Lett.<\/i> <b>2010<\/b>, <i>51<\/i>, 4886-4889. (SCI, IF<sub>2008<\/sub> = 2.568, 21\/55)<\/li>\n<li>Tseng CH, Tzeng CC, Yang CL, Lu PJ, Chen HL, Li HY, Chuang YC, Yang CN, <b>Chen YL<\/b>* \u201cSynthesis and antiproliferative evaluation of certain indeno[1,2-<i>c<\/i>]quinoline derivatives. Part 2\u201d <i>J. Med. Chem.<\/i> <b>2010<\/b>, 53, 6164-6179. (SCI, IF<sub>2009<\/sub> = 4.802, 3\/46)<\/li>\n<li>Tseng CH, <b>Chen YL<\/b>, Yang SH, Peng SI, Cheng CM, Han CH, Lin SR, Tzeng CC* \u201cSynthesis and antiproliferative evaluation of certain iminonaphtho[2,3-<i>b<\/i>]furan derivatives\u201d<i> Bioorg. Med. Chem.<\/i> <b>2010<\/b>, <i>18<\/i>, 5172-5182. (SCI, IF<sub>2009<\/sub> = 2.822, 17\/46)<\/li>\n<li>Chiu CC,* Chen JYF, Lin KL, Huang CJ, Chen WY, Han LY, Tseng CH, <b>Chen YL<\/b>,* Lin SR \u201cp38 MAPK and NF\u03baB pathways are involved in Naphtho[1,2-<i>b<\/i>] furan-4,5-dione induced anti-proliferation and apoptosis of human hepatoma cells\u201d <i>Cancer Lett.<\/i> <b>2010<\/b>, <i>295<\/i>, 92-99. (SCI, IF<sub>2009<\/sub> = 3.741, 52\/166)<\/li>\n<li>Lin KL, Su JC, Chien CM, Tseng CH, <b>Chen YL<\/b>, Chang LS, Lin SR\u00a0 \u201cNaphtho[1,2-b]furan-4,5-dione disrupts Janus kinase-2 and induces apoptosis in breast cancer MDA-MB-231 cells\u201d <i>Toxicol. In Vitro, <\/i><b>2010<\/b>, <i>24<\/i>, 1158-1167. (SCI, IF<sub>2009<\/sub> = 2.060, 44\/77)<\/li>\n<li>Chien CM, Lin KL, Su JC, Chuang PW, Tseng CH, <b>Chen YL<\/b>, Chang LS, Lin SR \u201cNaphtho[1,2-<i>b<\/i>]furan-4,5-dione induces apoptosis of oral squamous cell carcinoma: Involvement of EGF receptor\/PI3K\/Akt signaling pathway\u201d <i>Eur. J. Pharmacol. <\/i><b>2010<\/b><i>, 636<\/i>, 52-58. (SCI, IF<sub>2008<\/sub> = 2.787, 78\/219)<\/li>\n<li>Yang PM, Huang WC, Lin YC, Huang WY, Wu HA, Chen WL, Chang YF, Chou CW, Tzeng CC, <b>Chen YL<\/b>, Chen CC \u201cLoss of IKK beta activity increases p53 stability and p21 expression leading to cell cycle arrest and apoptosis\u201d <i>J. Cell. Mol. Med. <\/i><b>2010<\/b>, <i>14<\/i>, 687-698. (SCI, IF<sub>2008<\/sub> = 5.114, 8\/83)<\/li>\n<li>Chang MY, Lin CH, <b>Chen YL<\/b>, Hsu RT, Chang CY \u201cBF<sub>3<\/sub>-promoted synthesis of spiroindenyl heterocycles\u201d <i>Tetrahedron Lett.<\/i> <b>2010<\/b>, <i>51<\/i>, 3154-3158. (SCI, IF<sub>2008<\/sub> = 2.568, 21\/55)<\/li>\n<li>Chang MY, Lin CH, <b>Chen YL<\/b>, Chang CY, Hsu RT \u201cBF<sub>3<\/sub>-Promoted Synthesis of Diarylhexahydrobenzo[<i>f<\/i>]isoquinoline\u201d <i>Org. Lett.<\/i>.<b> 2010<\/b>,<i> 12<\/i>, 1176-1179. (SCI, IF<sub>2008<\/sub> = 5.128, 4\/55)<\/li>\n<li>Lu CM, <b>Chen YL<\/b>, Chen HL, Chen CA, Lu PJ, Yang CN, Tzeng CC* \u201cSynthesis and Antiproliferative Evaluation of Certain Indolo[3,2-<i>c<\/i>]quinoline Derivatives\u201d <i>Bioorg. Med. Chem.<\/i> <b>2010<\/b>, <i>18<\/i>, 1948-1957. (SCI, IF<sub>2009<\/sub> = 2.822, 17\/46)<\/li>\n<li>Su JC, Lin KL, Chien CM, Tseng CH, <b>Chen YL<\/b>, Chang LS, Lin SR \u201cNaphtho[1,2-b]furan-4,5-dione inactivates EGFR and PI3K\/Akt signaling pathways in human lung adenocarcinoma A549 cells\u201d <i>Life Sci.<\/i> <b>2010<\/b>, <i>86<\/i>, 207-213. (SCI, IF<sub>2008<\/sub> = 2.583, 33\/83)<\/li>\n<li>Chang MY, Lin CH, <b>Chen YL<\/b> \u201cSelenium dioxide-mediated methoxyhydroxylation of cyclic arylolefin\u201d <i>Tetrahedron Lett.<\/i> <b>2010<\/b>, <i>51<\/i>, 1430-1433. (SCI, IF<sub>2008<\/sub> = 2.568, 21\/55)<\/li>\n<li>Lin KL, Su JC, Chien CM, Tseng CH, <b>Chen YL<\/b>,* Chang LS, Lin SR*\u00a0 \u201cNaphtho[1,2-b]furan-4,5-dione induces apoptosis and S-phase arrest of MDA-MB-231 cells through JNK and ERK signaling activation\u201d <i>Toxicol. In Vitro, <\/i><b>2010<\/b>, <i>24<\/i>, 61-70. (SCI, IF<sub>2009<\/sub> = 2.060, 44\/77)<\/li>\n<li>Chang FS, Chen WC, Wang CH, Tzeng CC, <b>Chen YL<\/b>* \u201cSynthesis and antiproliferative evaluations of certain 2-phenylvinylquinoline (2-styrylquinoline) and 2-furanylvinylquinoline derivatives\u201d <i>Bioorg. Med. Chem.<\/i> <b>2010<\/b>, <i>18<\/i>, 124-133. (SCI, IF<sub>2009<\/sub> = 2.822, 17\/46)<\/li>\n<li>Yang CL, Tseng CH, <b>Chen YL<\/b>, Lu CM, Kao CL, Wu MH, Tzeng CC \u201cIdentification of benzofuro[2,3-<i>b<\/i>]quinoline derivatives as a new class of antituberculosis agents\u201d <i>Eur. J. Med. Chem.<\/i><b> <\/b><b>2010<\/b>, <i>45<\/i>,<b> <\/b>602-607. (SCI, IF<sub>2009<\/sub> = 3.269, 10\/46)<\/li>\n<\/ol>\n<p align=\"center\"><b>2009<\/b><\/p>\n<ol>\n<li>Su JC, Lin KL, Chien CM, Lu CM, <b>Chen YL<\/b>, Chang LS, Lin SR* \u201cNovel indoloquinoline derivative, IQDMA, induces G2\/M phase arrest and apoptosis in A549 cells through JNK\/p38 MAPK signaling activation\u201d <i>Life Sci.<\/i> <b>2009<\/b>, <i>85,<\/i> 505-516. (SCI, IF<sub>2008<\/sub> = 2.583, 33\/83)<\/li>\n<li>Tseng CH, <b>Chen YL<\/b>, Chung KY, Cheng CM, Wang CH, Tzeng CC* \u201cSynthesis and antiproliferative evaluation of 6-arylindeno[1,2-<i>c<\/i>]quinoline derivatives\u201d<i> Bioorg. Med. Chem.<\/i> <b>2009<\/b>, <i>17<\/i>, 7465-7476. (SCI, IF<sub>2008<\/sub> = 3.078, 12\/55)<\/li>\n<li>Wu PC, Huang YB, Chang CK, <b>Chen YL<\/b>, Tzeng CC, Tsai YH* \u201cHighly sensitive quantitative analysis of 1-[3-(Furo[3,2-c]quinolin-4-ylamino)phenyl]-<\/li>\n<\/ol>\n<p>ethanone oxime, a new antitumor agent, in rat plasma by LC with electrochemical detection\u201d <i>Chromatographia.<\/i> <b>2009<\/b>, <i>70<\/i>, 265-269. (SCI, IF<sub>2008<\/sub> = 1.312, 44\/70)<\/p>\n<ol>\n<li>Tseng CH, Lin CS, Shih PK, Tsao LT, Wang JP, Cheng CM, Tzeng CC, <b>Chen YL*<\/b> \u201cFuro[3&#8242;,2&#8242;:3,4]naphtho[1,2-<i>d<\/i>]imidazole Derivatives as Potential Inhibitors of Inflammatory Factors in Sepsis\u201d <i>Bioorg. Med. Chem.<\/i> <b>2009<\/b>, <i>17<\/i>, 6773-6779. (SCI, IF<sub>2008<\/sub> = 3.078, 12\/55)<\/li>\n<li>Hsien KC, Chen HT, Chen YC, <b>Chen YL<\/b>, Lu CY, Kao CL* \u201cPyridoxal 5&#8242;-Phosphate Binding in Lysine-Modified PAMAM Dendrimers: A Biomimetic Approach\u201d <i>Org. Lett.<\/i>.<b> 2009<\/b>,<i> 11<\/i>, 3526-3529. (SCI, IF<sub>2008<\/sub> = 5.128, 4\/55)<\/li>\n<li>Tseng CH, <b>Chen YL<\/b>, Lu CM, Wang CK, Tsai YT, Lin RW, Chen CF, Chang YF, Wang GJ, Ho ML, Tzeng CC* \u201cSynthesis and Anti-osteoporotic Evaluation of Certain 3-Amino-2-hydroxypropoxyisoflavone Derivatives\u201d <i>Eur. J. Med. Chem. <\/i><b>2009<\/b>, <i>44<\/i>,<i> <\/i>3621-3626. (SCI, IF<sub>2008<\/sub> = 2.882, 13\/40)<\/li>\n<li>Lee CH, Hu WP, Hong CH, Yu HS, Liao WT, Chen CY, <b>Chen YL<\/b>, Chen BH, Chen GS, Wang JJ* \u201cPyrrolo[2,1-c][1,4]benzodiazepine and indole conjugate (IN6CPBD) has better efficacy and superior safety than the mother compound DC-81 in suppressing the growth of established melanoma in vivo\u201d <i>Chem.-Biol. Interact.<\/i>, <b>2009<\/b>, <i>180<\/i>(3), 360-367. (SCI, IF<sub>2008<\/sub> = 3.007, 18\/75)<\/li>\n<li><b>Chen YL<\/b>, Chen YW, Lo WF, Kao CL, Liu YS, Yao CW, Tzeng CC* \u201cSynthesis and antimycobacterial evaluation on arylsulfonyl and arylcarbonyl derivatives of ofloxacin\u201d <i>J. Chin. Chem. Soc.<\/i>, <b>2009<\/b>, <i>55<\/i>, 374-380. (SCI, IF<sub>2008<\/sub> = 0.770, 80\/125)<\/li>\n<li>Huang YL, Cheng YH, Hsien KC, <b>Chen YL<\/b>, Kao CL* \u201cConcise bromodecarboxylation of cinnamic acids to b-bromostyrenes\u201d <i>Tetrahrdron Lett.<\/i><b> <\/b><b>2009<\/b>, <i>50<\/i>, 1834-1837. (SCI, IF<sub>2008<\/sub> = 2.538, 21\/55)<\/li>\n<li>Hu WP, Liang JJ, Kao CL, Chen YC, Chen CY, Tsai FY, Wu MJ, Chang LS, <b>Chen YL<\/b>, Wang JJ* \u201cSynthesis and antitumor activity of novel enediyne-linked pyrrolo[2,1-c][1,4]benzodiazepine hybrids\u201d <i>Bioorg. &amp; Med. Chem.<\/i> <b>2009<\/b>, <i>17<\/i>, 1172-1180. (SCI, IF<sub>2008<\/sub> = 3.078, 12\/55)<\/li>\n<\/ol>\n<p align=\"center\"><b>2008<\/b><\/p>\n<ol>\n<li>Yang SH, Chien CM, Su JC, <b>Chen YL<\/b>, Chang LS, Lin SR \u201cNovel indoloquinoline derivative, IQDMA, inhibits STAT5 signaling associated with apoptosis in K562 cells\u201d <i>J. of Biochem.. Mol. Toxic.<\/i> <b>2008<\/b>, <i>22<\/i>, 396-404.<\/li>\n<li>Chien CM, Yang SH, Lin KL, <b>Chen YL<\/b>, Chang LS, Lin SR \u201cNovel indoloquinoline derivative, IQDMA, suppresses STAT5 phosphorylation and induces apoptosis in HL-60 cells\u201d <i>Chem.-Biol. Interact.<\/i> <b>2008<\/b>, <i>176<\/i>, 40-47.<\/li>\n<li>Tseng CH, <b>Chen YL<\/b>, Lu PJ, Yang CN, Tzeng CC \u201cSynthesis and antiproliferative evaluation of certain indeno[1,2-<i>c<\/i>]quinoline derivatives\u201d <i>Bioorg. &amp; Med. Chem.<\/i> <b>2008<\/b>, <i>16<\/i>, 3151-3162. (SCI, IF<sub>2007<\/sub> = 2.662)<\/li>\n<li><b>Chen YL<\/b>, Lin HC, Yang CN, Lu PJ, Tzeng CC \u201cSynthesis and antiproliferative evaluation of 4-anilino-n-methoxyfuro[2,3-b]quinoline derivatives (n = 6, 7). Part 5\u201d<i> Chem. &amp; Biodiv.<\/i> <b>2008<\/b>, <i>4<\/i>, 267-278.<\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"<p>2013 Chen YL, Tseng CH, Lo YC, Lin RW, C &hellip; <a href=\"https:\/\/wp.kmu.edu.tw\/yeloch\/%e7%a0%94%e7%a9%b6%e8%91%97%e4%bd%9c\/\">\u95b1\u8b80\u5168\u6587 <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":18,"featured_media":0,"parent":0,"menu_order":1,"comment_status":"open","ping_status":"open","template":"onecolumn-page.php","meta":{"_exactmetrics_skip_tracking":false,"_exactmetrics_sitenote_active":false,"_exactmetrics_sitenote_note":"","_exactmetrics_sitenote_category":0,"footnotes":""},"class_list":["post-8","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/wp.kmu.edu.tw\/yeloch\/wp-json\/wp\/v2\/pages\/8","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/wp.kmu.edu.tw\/yeloch\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/wp.kmu.edu.tw\/yeloch\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/wp.kmu.edu.tw\/yeloch\/wp-json\/wp\/v2\/users\/18"}],"replies":[{"embeddable":true,"href":"https:\/\/wp.kmu.edu.tw\/yeloch\/wp-json\/wp\/v2\/comments?post=8"}],"version-history":[{"count":5,"href":"https:\/\/wp.kmu.edu.tw\/yeloch\/wp-json\/wp\/v2\/pages\/8\/revisions"}],"predecessor-version":[{"id":10,"href":"https:\/\/wp.kmu.edu.tw\/yeloch\/wp-json\/wp\/v2\/pages\/8\/revisions\/10"}],"wp:attachment":[{"href":"https:\/\/wp.kmu.edu.tw\/yeloch\/wp-json\/wp\/v2\/media?parent=8"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}