題目:
Iron-Catalyzed Oxidative Direct alpha-C-H Bond Functionalization of Cyclic Ethers: Selective C-O Bond Formation in the Presence of a Labile Aldehyde Group.
(高雄醫學大學張芳榮教授提供摘要)
ABSTRACT: Iron catalyzed oxidative coupling of salicylaldehydes with cyclic ethers proceeded through the direct α-C−H functionalization of ethers, forming the corresponding acetals in moderate to excellent yields. This is the first example of iron catalyzed selective C−O bond formation in the presence of a sensitive aldehyde moiety.
利用鐵催化於水楊醛與環醚反應進行醚類的α-C-H官能基修飾,高效率地形成縮醛衍生物。且第一個發表藉由鐵催化於具高活性的醛基結構上選擇性形成C−O鍵結之研究。